生物結合試劑

生物結合試劑 / 產品分組和此類別中的項目
Bioconjugation reagents: biotin, streptavidin, biotinylation reagents, bifunctional cross-linkers, PEG-linkers, auxiliary reagents for click chemistry, etc.

活化酯（双官能团）

Bifunctional activated NHS and STP esters for binding with primary and secondary amine groups.
分組標籤 Crosslinking, NHS esters, Cycloalkenes, Copper-free click chemistry, STP esters, Biotinylation, Cycloalkynes, Maleimides, Azides, Alkynes, Click chemistry, Protein labeling

炔烃

Various terminal alkynes for сlick сhemistry. Fluorescent dye alkynes are listed under 'Reactive dyes' category.
分組標籤 Crosslinking, NHS esters, STP esters, Biotinylation, Maleimides, Carboxylic acids, Alkynes, Halides, Hydrazides, Click chemistry, Protein labeling, Amines
  • Alkyne-PEG2-NHS ester
    Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on diethyleneglycol (PEG2).
  • Alkyne-PEG2-amine
    Diethyleneglycol (PEG2) based bifunctional linker containing amine and alkyne functional groups.
  • Alkyne-PEG2-carboxylic acid
    Bifunctional diethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
  • Alkyne-PEG2-iodide
    Bifunctional reactive crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling, and reactive alkyl iodide group.
  • Alkyne-PEG3-NHS ester
    Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on triethyleneglycol (PEG3).
  • Alkyne-PEG3-OH
    Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.
  • Alkyne-PEG3-amine
    Alkyne-PEG3-amine is a medium-length heterobifunctional linker for conjugation.
  • Alkyne-PEG3-carboxylic acid
    Bifunctional triethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
  • Alkyne-PEG3-iodide
    PEG3 with alkyne and iodide functional groups, a reactive and hydrophilic linker for alkylation and click chemistry.
  • Alkyne-PEG4-NHS ester
    Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on tetraethyleneglycol (PEG4).
  • Alkyne-PEG4-amine
    A bifunctional linker molecule containing both terminal alkyne moiety for click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.
  • Alkyne-PEG4-carboxylic acid
    Bifunctional tetraethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
  • Alkyne-PEG4-iodide
    Bifunctional reactive PEG4-based crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling and reactive alkyl iodide group.
  • Alkyne-PEG4-maleimide
    Water soluble, heterobifunctional hydrophilic linker with a length of 14 Å, containing maleimide for thiol labeling, and alkyne for click chemistry. An ideal reagent to attach an alkyne moiety to a protein.
  • Biotin-PEG2-alkyne
    Biotin alkyne is a reagent for click chemistry labeling with biotin, an affinity probe to streptavidin.
  • Biotin-PEG4-alkyne
    Biotin alkyne is a reagent for click chemistry labeling with biotin, an affinity probe to streptavidin.
  • Hexynoic acid STP ester
    Alkyne activated ester for the modification of amine groups. STP ester group is an excellent alternative to NHS ester functionality.
  • 己酸NHS酯 (Hexynoic acid NHS ester)
    己酸 NHS 酯，用於銅催化點擊化學中帶有炔基的生物分子標記。
  • 戊烯酸STP酯 (Pentynoic acid STP ester)
    一種活化酯, 用於將炔基引入肽/蛋白質和連結反應。
  • 炔基馬來酰亞胺 (Alkyne maleimide)
    馬來酰亞胺試劑用於將炔基官能團連接到蛋白質、多肽和其它含有 SH（硫醇）基團的分子上，包括半胱氨酸殘基。
  • 炔烴-PEG3-馬來酰亞胺
    具有炔基和馬來酰亞胺基團的雙功能間隔基。
  • 炔醯肼 (Alkyne hydrazide)
    含有炔基和醯肼官能團的雙功能試劑。它與醛和酮發生反應。然後炔基可以通過 CuAAC 反應與各種疊氮化物偶聯。

环烯烃

Cycloalkenes for copper-free alkene-tetrazine click reaction.
分組標籤 NHS esters, Cycloalkenes, Copper-free click chemistry, Protein labeling

胺类

Amines for the coupling with various electrophilic compounds like activated esters and epoxides.
分組標籤 Crosslinking, PROTAC, Copper-free click chemistry, Biotinylation, Cycloalkynes, Carboxylic acids, Azides, Alkynes, Click chemistry, Amines
  • (S,R,S)-AHPC-PEG2-C2-amine
    Degrader building block containing an E3 ligase ligand with linker and amino group for conjugation with other functionalized linkers and target protein ligands.
  • 3-Azidopropylamine hydrochloride
    A bifunctional short linker with amino and azido groups. A solid, chemically stable hydrochloride form of azidopropylamine. This product is ideal as an azidopropylamine bulk for applications when a large amount of reagent is needed.
  • Alkyne-PEG2-amine
    Diethyleneglycol (PEG2) based bifunctional linker containing amine and alkyne functional groups.
  • Alkyne-PEG3-amine
    Alkyne-PEG3-amine is a medium-length heterobifunctional linker for conjugation.
  • Alkyne-PEG4-amine
    A bifunctional linker molecule containing both terminal alkyne moiety for click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.
  • Amine-PEG2-carboxylic acid
    Hydrophilic PEG2-linker with a terminal amino group and a carboxyl group.
  • Amine-PEG3-OH
    Bifunctional PEG3 derivative with amine and hydroxyl groups.
  • Amine-PEG3-carboxylic acid
    Hydrophilic PEG3-linker with a terminal amino group and a carboxyl group.
  • Azide-PEG2-amine
    A diethylene glycol (PEG2) linker with azide and amino groups.
  • Azide-PEG3-amine
    A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)
  • Azide-PEG4-amine
    PEG4 amine azide is a bifunctional linker with amine and azide functional groups. It is based on a tetraethyleneglycol core. The length of the PEG4 linker is 1.4 nm.
  • Biotin-PEG2-amine
    Diethylene glycol (PEG2) based bifunctional molecule containing biotin and amine functional group.
  • Biotin-PEG3-amine
    Triethylene glycol (PEG3) based bifunctional molecule containing biotin and amine functional group.
  • Biotin-PEG4-amine
    Tetraethylene glycol (PEG4) based bifunctional molecule containing biotin and amine functional group.
  • DBCO-amine trifluoroacetate
    Bifunctional linker containing dibenzocyclooctyne (DBCO, ADIBO) for strain-promoted copper-free click reaction (SPAAC) and free amine for the coupling with various electrophilic compounds like activated esters and epoxides.
  • Thalidomide-O-PEG2-amine
    Thalidomide-containing building block with PEG2-linker and amino group for conjugation with other functionalized linkers and target protein ligands.
  • VHL Ligand 1 dihydrochloride
    VHL Ligand 1 is a building block for synthesizing proteolysis-targeting chimera (PROTAC) molecules.
  • 氨基-PEG6-醇 (Amine-PEG6-OH)
    具有末端氨基和羥基的親水性六乙二醇衍生物。
  • 胺-PEG4-OH (Amine-PEG4-OH)
    一種具有末端氨基和羥基的親水性四甘醇衍生物。
  • 胺-PEG4-羧酸 (Amine-PEG4-carboxylic acid)
    具有末端氨基和羧基的親水性 PEG4 連接體。
  • 鹽酸四甘氨酸 (Tetraglycine hydrochloride)
    四甘氨酸是由4個甘氨酸單體組成的寡肽。基於氨基和羧基，它被用作雙功能接頭。

叠氮化物

Various non-fluorescent azides for click chemistry. Fluorescent azides are listed under Reactive dyes category.
分組標籤 Crosslinking, PROTAC, NHS esters, Copper-free click chemistry, Tetrazines, Biotinylation, Maleimides, Carboxylic acids, Azides, Halides, Click chemistry, Protein labeling, Amines

生物素和链霉亲和素

Biotin derivatives with different spacers for introducing biotin labels into proteins, antibodies, and nucleic acids. Fluorescent dye conjugates of biotin and streptavidin.
分組標籤 AF 488, Crosslinking, NHS esters, Copper-free click chemistry, Tetrazines, Biotinylation, AF 594, Maleimides, Carboxylic acids, Neuroscience, Azides, Flow cytometry, Alkynes, Halides, Hydrazides, sulfo-Cyanine3, Microscopy, Click chemistry, Super-resolution imaging, sulfo-Cyanine5, Protein labeling, Amines, AMCA
  • AF 488 streptavidin
    AF 488 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • AF 594 streptavidin
    AF 594 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • AMCA鏈黴親和素 (AMCA streptavidin)
    一種鏈黴親和素的 AMCA 偶聯物（高親和力生物素結合蛋白），用於免疫螢光、蛋白質印跡、微孔板測定和其他應用。
  • Biocytin hydrochloride
    Lysine derivative of biotin for conjugation with avidin or streptavidin, neuroanatomical tracer.
  • Biotin-PEG2-alkyne
    Biotin alkyne is a reagent for click chemistry labeling with biotin, an affinity probe to streptavidin.
  • Biotin-PEG2-azide
    Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe to streptavidin.
  • Biotin-PEG3-amine
    Triethylene glycol (PEG3) based bifunctional molecule containing biotin and amine functional group.
  • Biotin-PEG4-NHS ester
    PEG4-containing activated ester for simple and efficient biotin labeling of antibodies, proteins, and other primary amine-containing biomolecules.
  • Biotin-PEG4-alkyne
    Biotin alkyne is a reagent for click chemistry labeling with biotin, an affinity probe to streptavidin.
  • Biotin-PEG4-amine
    Tetraethylene glycol (PEG4) based bifunctional molecule containing biotin and amine functional group.
  • Biotin-PEG4-azide
    Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe to streptavidin.
  • Biotin-PEG4-carboxylic acid
    Bifunctional tetraethyleneglycol linker with biotin and carboxylic acid moieties.
  • Biotin-PEG4-iodide
    A highly reactive biotinylation reagent that readily and efficiently interacts with various nucleophiles.
  • Biotin-PEG4-tetrazine
    Biotin tetrazine is a reagent for copper-free click chemistry labeling with biotin, a well-known affinity probe to streptavidin.
  • Biotin-X-NHS ester
    Biotin derivative with C6-spacer to reduce steric effect when binding amino acids, peptides, or proteins by reacting with primary amines.
  • Biotin-X-hydrazide
    Hydrazide biotin reagent with aminocaproic spacer useful for biotinylation of macromolecule reactive carbonyls.
  • Biotin-cystamine hydrochloride
    Biotin and cystamine conjugate is a cleavable biotinylation reagent.
  • sulfo-Cyanine3 streptavidin
    sulfo-Cyanine3 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • sulfo-Cyanine3-PEG3-biotin
    Conjugate of hydrophilic sulfo-Cyanine3 dye with biotin, affinity label for avidin/streptavidin.
  • sulfo-Cyanine5-PEG3-biotin
    Biotin conjugate of the far-red fluorescent sulfo-Cyanine5 dye.
  • sulfo-Cyanine5鏈黴親和素 (sulfo-Cyanine5 streptavidin)
    鏈黴親和素的sulfo-Cyanine5 偶聯物，是一種高親和力的生物素結合蛋白，用於免疫螢光、蛋白質印跡、酶標儀和其他應用。
  • 生物素 X 馬來酰亞胺 (Biotin X-maleimide)
    硫醇反應性雙功能連接子，用於將生物素連接到蛋白質、多肽和其他巰基化分子上。
  • 生物素-PEG3-OH (Biotin-PEG3-OH)
    具有生物素和羥基的雙功能三乙二醇連接子。
  • 生物素-PEG3-疊氮化物 (Biotin-PEG3-azide)
    生物素疊氮化物是一種用生物素進行點擊化學標記的試劑，生物素是一種著名的鏈霉親和素親和探針。
  • 生物素-XX-NHS酯 (Biotin-XX-NHS ester)
    生物素衍生物，長的間隔基可減少空間效應，可通過與伯胺反應與氨基酸、肽或蛋白質結合。
  • 生物素炔 (Biotin alkyne)
    生物素炔是一種反應性親和標記物，可以通過點擊反應附著到生物分子上。

酰肼

Hydrazides are carbonyl-reactive reagents for the labeling of aldehydes and ketones.
分組標籤 Crosslinking, Biotinylation, Azides, Alkynes, Hydrazides, Click chemistry, Protein labeling
  • Azide-PEG4-hydrazide
    A bifunctional reagent containing the azide group and hydrazide function. It reacts with aldehydes and ketones. The azide group can then be coupled with various alkynes via CuAAC reaction.
  • Biotin-X-hydrazide
    Hydrazide biotin reagent with aminocaproic spacer useful for biotinylation of macromolecule reactive carbonyls.
  • 炔醯肼 (Alkyne hydrazide)
    含有炔基和醯肼官能團的雙功能試劑。它與醛和酮發生反應。然後炔基可以通過 CuAAC 反應與各種疊氮化物偶聯。

四嗪

Non-fluorescent tetrazines for inverse electron demand Diels-Alder reaction (IEDDA) with terminal alkenes and strained olefins, such as trans-cyclooctenes and some cyclooctynes.
分組標籤 Crosslinking, Copper-free click chemistry, Tetrazines, Biotinylation, Azides, Click chemistry
  • Azide-PEG3-tetrazine
    A hydrophilic bifunctional linker with azide and tetrazine function groups flanking PEG3 (triethylene glycol) spacer.
  • Biotin-PEG4-tetrazine
    Biotin tetrazine is a reagent for copper-free click chemistry labeling with biotin, a well-known affinity probe to streptavidin.
  • PEG3-tetrazine
    PEG3 tetrazine is a mono-reactive triethyleneglycol with a tetrazine group for IEDDA conjugation with strained olefins.

羧酸

Carboxylic acids with reactive groups for the conjugation of different biomolecules.
分組標籤 Crosslinking, PROTAC, Carboxylic acids, Azides, Alkynes, Halides, Click chemistry, Amines

鹵化物

Halogen derivatives with reactive groups for bioconjugation.
分組標籤 Crosslinking, Carboxylic acids, Azides, Alkynes, Halides, Click chemistry
  • Alkyne-PEG2-iodide
    Bifunctional reactive crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling, and reactive alkyl iodide group.
  • Alkyne-PEG3-iodide
    PEG3 with alkyne and iodide functional groups, a reactive and hydrophilic linker for alkylation and click chemistry.
  • Alkyne-PEG4-iodide
    Bifunctional reactive PEG4-based crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling and reactive alkyl iodide group.
  • Azide-PEG2-iodide
    A bifunctional molecule containing hydrophilic PEG2 with azide and iodide groups.
  • Azide-PEG3-chloride
    Azide-PEG3-chloride contains a reactive halogen atom and an azide group for click chemistry reaction. It can also serve as a protected amine group equivalent.
  • Azide-PEG3-iodide
    Azide-PEG3-iodide is a bifunctional linker with a highly reactive alkylative halogen functional group and an azido group for click chemistry or Staudinger ligation.
  • Iodo-PEG3-carboxylic acid
    A bifunctional compound containing carboxylic acid functional group, and iodide, an active halogen group.
  • Iodo-PEG3-iodide
    Homobifunctional PEG3 based linker with halogen reactive groups is useful for the crosslinking of nucleophiles.

點擊化學配體和催化劑

Auxiliary reagents for click chemistry: catalysts, buffers, and ligands for copper-catalyzed click reaction (CuAAC).
分組標籤 Click chemistry

生物結合輔助試劑

Auxiliary reagents, various buffers, and solvents for labeling and conjugation.
分組標籤 Click chemistry

同型雙功能試劑

Homobifunctional crosslinkers with identical reactive groups at opposite ends of the spacer for intramolecular crosslinks and chemical crosslinking of macromolecular chains.
分組標籤 Crosslinking, NHS esters, Carboxylic acids, Azides, Halides, Click chemistry

馬來酰亞胺

Maleimides are thiol-reactive compounds for labeling sulfhydryl (thiol) groups in proteins.
分組標籤 Crosslinking, NHS esters, Copper-free click chemistry, Biotinylation, Cycloalkynes, Maleimides, Azides, Alkynes, Click chemistry

環炔烴

Highly reactive cycloalkynes for copper-free click reaction (SPAAC, strain-promoted azide-alkyne cycloaddition).
分組標籤 Crosslinking, NHS esters, Copper-free click chemistry, STP esters, Cycloalkynes, Maleimides, Cyanine3, Click chemistry, Protein labeling, Amines
  • 3269-x，Cy3-PEG4-BCN（外切） [Cy3-PEG4-BCN (exo)]
    Cyanine3-PEG4-BCN 是一種用於疊氮基修飾的乙二醇分離式連接體，用於無銅點擊偶聯。
  • DBCO-NHS 酯
    偶氮二苯並環辛炔 (DBCO、ADIBO) 試劑用於應變促進的無銅點擊化學 (SPAAC)。該試劑含有 NHS 酯官能團，用於將環辛炔連接到各種分子上。
  • DBCO-PEG6-NHS ester
    A heterobifunctional linker with DBCO and NHS ester function groups flanking PEG6 (hexaethylene glycol).
  • DBCO-STP酯 (DBCO-STP ester)
    一種活化酯用於蛋白質/抗體/肽的修飾，引入到無銅點擊化學反應。
  • DBCO-amine trifluoroacetate
    Bifunctional linker containing dibenzocyclooctyne (DBCO, ADIBO) for strain-promoted copper-free click reaction (SPAAC) and free amine for the coupling with various electrophilic compounds like activated esters and epoxides.
  • DBCO-馬來醯亞胺 (DBCO-maleimide)
    雙功能連接體含有硫醇反應性馬來醯亞胺基團和疊氮化物反應性二苯並環辛炔部分。
  • Exo-BCN-PNP
    BCN-PNP 碳酸酯是一種通過氨基甲酸酯與底物伯氨基連接引入 BCN 基團的工具。

硫醇類

Bifunctional reagents with a thiol (-SH) functional group. Thiols are nucleophilic compounds that participate in many reactions with electrophiles.
分組標籤 Crosslinking, Thiols
  • Hydroxy-PEG2-thiol
    Short bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.
  • Hydroxy-PEG3-thiol
    PEG3 bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.
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