生物結合試劑

生物結合試劑 / 產品分組和此類別中的項目
Bioconjugation reagents: biotin, streptavidin, biotinylation reagents, bifunctional cross-linkers, PEG-linkers, auxiliary reagents for click chemistry, etc.

活化酯

Bifunctional activated NHS and STP esters for binding with primary and secondary amine groups.
分組標籤 交聯, NHS酯類, Cycloalkenes, 無銅點擊化學, STP酯類, 生物素化, 環炔烴, 馬來酰亞胺, 疊氮化物, 炔烴, 點擊化學, Protein labeling

叠氮化物

Various non-fluorescent azides for click chemistry. Fluorescent azides are listed under Reactive dyes category.
分組標籤 交聯, PROTAC, NHS酯類, 無銅點擊化學, 四嗪類, 生物素化, 馬來酰亞胺, Carboxylic acids, 疊氮化物, Halides, 點擊化學, Protein labeling, 胺類

炔烃

Various terminal alkynes for сlick сhemistry. Fluorescent dye alkynes are listed under 'Reactive dyes' category.
分組標籤 交聯, NHS酯類, STP酯類, 生物素化, 馬來酰亞胺, Carboxylic acids, 炔烴, Halides, 醯肼類, 點擊化學, Protein labeling, 胺類
    • 戊烯酸STP酯 (Pentynoic acid STP ester)
      一種活化酯, 用於將炔基引入肽/蛋白質和連結反應。
    • Alkyne-PEG3-amine
      Alkyne-PEG3-amine is a medium-length heterobifunctional linker for conjugation.
    • Biotin-PEG4-alkyne
      Biotin alkyne is a reagent for click chemistry labeling with biotin, an affinity probe to streptavidin.
    • 炔烴-PEG3-馬來酰亞胺
      具有炔基和馬來酰亞胺基團的雙功能間隔基。
    • Alkyne-PEG2-carboxylic acid
      Bifunctional diethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
    • Alkyne-PEG4-iodide
      Bifunctional reactive PEG4-based crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling and reactive alkyl iodide group.
    • Alkyne-PEG4-carboxylic acid
      Bifunctional tetraethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
    • Hexynoic acid STP ester
      Alkyne activated ester for the modification of amine groups. STP ester group is an excellent alternative to NHS ester functionality.
    • Alkyne-PEG2-NHS ester
      Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on diethyleneglycol (PEG2).
    • Alkyne-PEG4-NHS ester
      Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on tetraethyleneglycol (PEG4).
    • Alkyne-PEG3-NHS ester
      Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on triethyleneglycol (PEG3).
    • 己酸NHS酯 (Hexynoic acid NHS ester)
      己酸 NHS 酯，用於銅催化點擊化學中帶有炔基的生物分子標記。
    • Alkyne-PEG3-iodide
      PEG3 with alkyne and iodide functional groups, a reactive and hydrophilic linker for alkylation and click chemistry.
    • Alkyne-PEG2-iodide
      Bifunctional reactive crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling, and reactive alkyl iodide group.
    • Alkyne-PEG2-amine
      Diethyleneglycol (PEG2) based bifunctional linker containing amine and alkyne functional groups.
    • Alkyne-PEG4-maleimide
      Water soluble, heterobifunctional hydrophilic linker with a length of 14 Å, containing maleimide for thiol labeling, and alkyne for click chemistry. An ideal reagent to attach an alkyne moiety to a protein.
    • Alkyne-PEG4-amine
      A bifunctional linker molecule containing both terminal alkyne moiety for click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.
    • Alkyne-PEG3-carboxylic acid
      Bifunctional triethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
    • Alkyne-PEG3-OH
      Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.
    • 炔醯肼 (Alkyne hydrazide)
      含有炔基和醯肼官能團的雙功能試劑。它與醛和酮發生反應。然後炔基可以通過 CuAAC 反應與各種疊氮化物偶聯。
    • 炔基馬來酰亞胺 (Alkyne maleimide)
      馬來酰亞胺試劑用於將炔基官能團連接到蛋白質、多肽和其它含有 SH（硫醇）基團的分子上，包括半胱氨酸殘基。
    • Biotin-PEG2-alkyne
      Biotin alkyne is a reagent for click chemistry labeling with biotin, an affinity probe to streptavidin.

環炔烴

Highly reactive cycloalkynes for copper-free click reaction (SPAAC, strain-promoted azide-alkyne cycloaddition).
分組標籤 交聯, NHS酯類, 無銅點擊化學, STP酯類, 環炔烴, 馬來酰亞胺, 花青3, 點擊化學, Protein labeling, 胺類
    • DBCO-NHS 酯
      偶氮二苯並環辛炔 (DBCO、ADIBO) 試劑用於應變促進的無銅點擊化學 (SPAAC)。該試劑含有 NHS 酯官能團，用於將環辛炔連接到各種分子上。
    • DBCO-STP酯 (DBCO-STP ester)
      一種活化酯用於蛋白質/抗體/肽的修飾，引入到無銅點擊化學反應。
    • 3269-x，Cy3-PEG4-BCN（外切） [Cy3-PEG4-BCN (exo)]
      Cyanine3-PEG4-BCN 是一種用於疊氮基修飾的乙二醇分離式連接體，用於無銅點擊偶聯。
    • DBCO-amine trifluoroacetate
      Bifunctional linker containing dibenzocyclooctyne (DBCO, ADIBO) for strain-promoted copper-free click reaction (SPAAC) and free amine for the coupling with various electrophilic compounds like activated esters and epoxides.
    • DBCO-PEG6-NHS ester
      A heterobifunctional linker with DBCO and NHS ester function groups flanking PEG6 (hexaethylene glycol).
    • Exo-BCN-PNP
      BCN-PNP 碳酸酯是一種通過氨基甲酸酯與底物伯氨基連接引入 BCN 基團的工具。
    • DBCO-馬來醯亞胺 (DBCO-maleimide)
      雙功能連接體含有硫醇反應性馬來醯亞胺基團和疊氮化物反應性二苯並環辛炔部分。

四嗪

Non-fluorescent tetrazines for inverse electron demand Diels-Alder reaction (IEDDA) with terminal alkenes and strained olefins, such as trans-cyclooctenes and some cyclooctynes.
分組標籤 交聯, 無銅點擊化學, 四嗪類, 生物素化, 疊氮化物, 點擊化學
    • Tetrazine-PEG3-OH
      Tetrazine-PEG3-OH is a mono-reactive triethyleneglycol with a tetrazine group for IEDDA conjugation with strained olefins.
    • Azide-PEG3-tetrazine
      A hydrophilic bifunctional linker with azide and tetrazine function groups flanking PEG3 (triethylene glycol) spacer.
    • Biotin-PEG4-tetrazine
      Biotin tetrazine is a reagent for copper-free click chemistry labeling with biotin, a well-known affinity probe to streptavidin.

环烯烃

Cycloalkenes for copper-free alkene-tetrazine click reaction.
分組標籤 交聯, NHS酯類, Cycloalkenes, 無銅點擊化學, Protein labeling

胺类

Amines for the coupling with various electrophilic compounds like activated esters and epoxides.
分組標籤 交聯, PROTAC, 無銅點擊化學, 生物素化, 環炔烴, Carboxylic acids, 疊氮化物, 炔烴, 點擊化學, 胺類

酰肼

Hydrazides are carbonyl-reactive reagents for the labeling of aldehydes and ketones.
分組標籤 交聯, 生物素化, 疊氮化物, 炔烴, 醯肼類, 點擊化學, Protein labeling
    • 炔醯肼 (Alkyne hydrazide)
      含有炔基和醯肼官能團的雙功能試劑。它與醛和酮發生反應。然後炔基可以通過 CuAAC 反應與各種疊氮化物偶聯。
    • Biotin-X-hydrazide
      Hydrazide biotin reagent with aminocaproic spacer useful for biotinylation of macromolecule reactive carbonyls.
    • 疊氮-PEG4-醯肼 (Azide-PEG4-hydrazide)
      含有疊氮基團和醯肼官能團的雙功能試劑。它與醛和酮發生反應。疊氮基團可以通過 CuAAC 反應與各種炔烴偶聯。

馬來酰亞胺

Maleimides are thiol-reactive compounds for labeling sulfhydryl (thiol) groups in proteins.
分組標籤 交聯, NHS酯類, 無銅點擊化學, 生物素化, 環炔烴, 馬來酰亞胺, 吲哚菁綠 (ICG) [Indocyanine Green (ICG)], 疊氮化物, 炔烴, 點擊化學

硫醇類

Bifunctional reagents with a thiol (-SH) functional group. Thiols are nucleophilic compounds that participate in many reactions with electrophiles.
分組標籤 交聯, 硫醇
    • Hydroxy-PEG3-thiol
      PEG3 bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.
    • Hydroxy-PEG2-thiol
      Short bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.

鹵化物

Halogen derivatives with reactive groups for bioconjugation.
分組標籤 交聯, 生物素化, Carboxylic acids, 疊氮化物, 炔烴, Halides, 點擊化學
    • Iodo-PEG3-carboxylic acid
      A bifunctional compound containing carboxylic acid functional group, and iodide, an active halogen group.
    • Azide-PEG3-chloride
      Azide-PEG3-chloride contains a reactive halogen atom and an azide group for click chemistry reaction. It can also serve as a protected amine group equivalent.
    • Iodo-PEG3-iodide
      Homobifunctional PEG3 based linker with halogen reactive groups is useful for the crosslinking of nucleophiles.
    • Alkyne-PEG2-iodide
      Bifunctional reactive crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling, and reactive alkyl iodide group.
    • Azide-PEG3-iodide
      Azide-PEG3-iodide is a bifunctional linker with a highly reactive alkylative halogen functional group and an azido group for click chemistry or Staudinger ligation.
    • Alkyne-PEG3-iodide
      PEG3 with alkyne and iodide functional groups, a reactive and hydrophilic linker for alkylation and click chemistry.
    • Alkyne-PEG4-iodide
      Bifunctional reactive PEG4-based crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling and reactive alkyl iodide group.
    • Azide-PEG2-iodide
      A bifunctional molecule containing hydrophilic PEG2 with azide and iodide groups.
    • Biotin-PEG4-iodide
      A highly reactive biotinylation reagent that readily and efficiently interacts with various nucleophiles.

羧酸

Carboxylic acids with reactive groups for the conjugation of different biomolecules.
分組標籤 交聯, PROTAC, 生物素化, Carboxylic acids, 疊氮化物, 炔烴, Halides, 點擊化學, 胺類

酒精类

Alcohols with reactive groups for the conjugation of different biomolecules.
分組標籤 交聯, 硫醇, 無銅點擊化學, 四嗪類, 生物素化, 疊氮化物, 炔烴, 點擊化學, 胺類
    • Alkyne-PEG3-OH
      Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.
    • Tetrazine-PEG3-OH
      Tetrazine-PEG3-OH is a mono-reactive triethyleneglycol with a tetrazine group for IEDDA conjugation with strained olefins.
    • Azide-PEG3-OH
      Azide-PEG3-OH is a bifunctional molecule with an azide group, primary alcohol, and a hydrophilic PEG3 linker in between.
    • Hydroxy-PEG3-thiol
      PEG3 bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.
    • Hydroxy-PEG2-thiol
      Short bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.
    • Azide-PEG4-OH
      Azide-PEG4-OH is a bifunctional molecule with an azide group, primary alcohol, and a hydrophilic PEG4 linker in between.
    • 胺-PEG4-OH (Amine-PEG4-OH)
      一種具有末端氨基和羥基的親水性四甘醇衍生物。
    • 3-Azidopropanol
      Azidopropanol is a short bifunctional linker compound with azide and hydroxyl functional groups.
    • Amine-PEG3-OH
      Bifunctional PEG3 derivative with amine and hydroxyl groups.
    • 疊氮化物-PEG6-OH (Azide-PEG6-OH)
      水溶性異質雙功能交聯劑，具有伯羥基、炔反應性疊氮基和 PEG6 親水連接基。
    • 氨基-PEG6-醇 (Amine-PEG6-OH)
      具有末端氨基和羥基的親水性六乙二醇衍生物。
    • 生物素-PEG3-OH (Biotin-PEG3-OH)
      具有生物素和羥基的雙功能三乙二醇連接子。

生物素

Biotin derivatives with different spacers for introducing biotin labels into proteins, antibodies, and nucleic acids.
分組標籤 交聯, NHS酯類, 無銅點擊化學, 四嗪類, 生物素化, 馬來酰亞胺, Carboxylic acids, 神經科學, 疊氮化物, 炔烴, Halides, 醯肼類, 磺基-花菁3, 顯微鏡觀察, 點擊化學, 磺基-花菁5, Tyramides, Protein labeling, 胺類

同型雙功能試劑

Homobifunctional crosslinkers with identical reactive groups at opposite ends of the spacer for intramolecular crosslinks and chemical crosslinking of macromolecular chains.
分組標籤 交聯, NHS酯類, Carboxylic acids, 疊氮化物, Halides, 點擊化學

點擊化學配體和催化劑

Auxiliary reagents for click chemistry: catalysts, buffers, and ligands for copper-catalyzed click reaction (CuAAC).
分組標籤 點擊化學

生物結合輔助試劑

Auxiliary reagents, various buffers, and solvents for labeling and conjugation.
分組標籤 點擊化學
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