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Alkyne-PEG4-maleimide

炔烴馬來酰亞胺 Click chemistry Crosslinking

貨號	數量	價格	交貨時間	購買此產品
2002-100mg	100 mg	$150	現貨
2002-1g	1 g	$590	現貨

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When proteins or other sensitive biomolecules need to be conjugated, polyethyleneglycol (PEG) linkers are a great choice. They provide hydrophilicity and maintain separation between conjugated molecules. This linker based on PEG4, has length of 14Å (1.4 nm). Heterobifunctional linkers carrying different reactive groups can be used to prepare cross-conjugates between different molecules.

Maleimide functional group is especially useful, because they can label proteins site specifically. Most proteins have only limited number of cysteine residues that selectively react with maleimides. Alkyne group can be then conjugated with azides in a selective copper-catalyzed process, CuAAC (copper-catalyzed alkyne-azide cycloaddition).

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建議協議

Conjugation of Alkyne- or Azide-modified Proteins with Dye Azides or Alkynes

Maleimide Labeling of Proteins and Other Thiolated Biomolecules

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FAM 疊氮化物, 5-異構體 (FAM azide, 5-isomer)

FAM（熒光素）疊氮化物，純 5-異構體，用於連結化學標記，。

DBCO-PEG6-NHS ester

A heterobifunctional linker with DBCO and NHS ester function groups flanking PEG6 (hexaethylene glycol).

炔基馬來酰亞胺 (Alkyne maleimide)

馬來酰亞胺試劑用於將炔基官能團連接到蛋白質、多肽和其它含有 SH（硫醇）基團的分子上，包括半胱氨酸殘基。

General properties

Appearance:	yellow oil
Mass spec M+ increment:	311.3
Molecular weight:	311.33
CAS number:	1262681-30-0
Molecular formula:	C₁₅H₂₁NO₆
Solubility:	good in water, DMF, DMSO
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	下載
	產品規格

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.