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Alkyne-PEG4-maleimide

炔烴 Click chemistry 馬來酰亞胺 Crosslinking

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2002-100mg	100 mg	$150	現貨
2002-1g	1 g	$590	現貨

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When proteins or other sensitive biomolecules need to be conjugated, polyethyleneglycol (PEG) linkers are a great choice. They provide hydrophilicity and maintain separation between conjugated molecules. This linker based on PEG4, has length of 14Å (1.4 nm). Heterobifunctional linkers carrying different reactive groups can be used to prepare cross-conjugates between different molecules.

Maleimide functional group is especially useful, because they can label proteins site specifically. Most proteins have only limited number of cysteine residues that selectively react with maleimides. Alkyne group can be then conjugated with azides in a selective copper-catalyzed process, CuAAC (copper-catalyzed alkyne-azide cycloaddition).

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建議協議

Conjugation of Alkyne- or Azide-modified Proteins with Dye Azides or Alkynes

Maleimide Labeling of Proteins and Other Thiolated Biomolecules

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BDP® 630/650 羧酸 (BDP® 630/650 carboxylic acid)

BDP 630/650 是一種明亮的螢光團，適用於光譜的遠紅外部分。這種染料非常適合顯微鏡和螢光偏振測定。這是一種可以活化用於偶聯的羧酸，或用作對照。

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EDC（N-乙基-N'-（3-二甲基氨基丙基）碳二亞胺），偶聯等級

水溶性碳二亞胺，用於羧酸與胺的偶聯。

FAM 疊氮化物, 5-異構體 (FAM azide, 5-isomer)

FAM（熒光素）疊氮化物，純 5-異構體，用於連結化學標記，。

General properties

Appearance:	yellow oil
Mass spec M+ increment:	311.3
Molecular weight:	311.33
CAS number:	1262681-30-0
Molecular formula:	C₁₅H₂₁NO₆
Solubility:	good in water, DMF, DMSO
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	下載
	產品規格

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.