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TCO-PEG4-NHS ester (axial isomer)

NHS esters Protein labeling Cycloalkenes Copper-free click chemistry
貨號 數量 價格 交貨時間
3056-10mg 10 mg $145 現貨
3056-25mg 25 mg $225 現貨
3056-100mg 100 mg $550 現貨
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TCO-PEG4-NHS ester is a bifunctional linker with trans-cyclooctene (TCO) and NHS ester groups flanking PEG4 (tetraethylene glycol).

The PEG spacer increases solubility in aqueous media and provides a long and flexible connection that minimizes steric hindrance involved with ligation.

The amine-reactive N-hydroxysuccinimide residue provides easy attachment to almost any primary or secondary amine group, such as protein, peptide, or small molecule amine.

Trans-cyclooctene readily reacts with tetrazines via inverse electron-demand Diels-Alder cycloaddition (IEDDA). TCO-Tetrazine ligation possesses ultrafast kinetics, selectivity, and long-term aqueous stability, which is important in low-concentration applications such as protein-protein conjugations, etc.

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偶氮二苯並環辛炔 (DBCO、ADIBO) 試劑用於應變促進的無銅點擊化學 (SPAAC)。該試劑含有 NHS 酯官能團，用於將環辛炔連接到各種分子上。

Ac4ManNAz (N-Azidoacetylmannosamine-tetraacylated)

An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.

General properties

Appearance: colorless syrup
Molecular weight: 514.57
CAS number: 1621096-79-4
Molecular formula: C24H38N2O10
Solubility: DMSO, DMF, THF, Acetonitrile, Dichloromethane
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
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產品規格
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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