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Alkyne-PEG3-carboxylic acid

炔烴 Carboxylic acids 點擊化學交聯

貨號	數量	價格	交貨時間
1743-1g	1 g	$490	現貨
1743-5g	5 g	$980	現貨
1743-25g	25 g	請查詢	現貨

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Alkyne-PEG3-carboxylic acid is a bifunctional triethyleneglycol derivative bearing a carboxy group and an alkyne moiety. The former can be activated with peptide coupling reagents like PyBOP or carbodiimides like EDC to form a stable amide linkage with amines. The alkyne group can be coupled with azides in a CuAAC reaction.

PEGs are hydrophilic linkers useful in synthesizing water-soluble conjugates.

以
ChemDraw 格式下載

建議協議

Conjugation of Alkyne- or Azide-modified Proteins with Dye Azides or Alkynes

計算機

解决方案计算器

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General properties

Appearance:	colorless to yellow oil
Molecular weight:	246.26
CAS number:	1415800-32-6
Molecular formula:	C₁₁H₁₈O₆
IUPAC name:	3,6,9,12-tetraoxapentadecyn-15-oic acid
Solubility:	good in most organic solvents and water
Quality control:	NMR ¹H, GC-MS (95%, as Me ester)
Storage conditions:	Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	下載
	產品規格

產品引用

Petrov, R.A.; Mefedova, S.R.; Yamansarov, E.Y.; Maklakova, S.Y.; Grishin, D.A.; Lopatukhina, E.V.; Burenina, O.Y.; Lopukhov, A.V.; Kovalev, S.V.; Timchenko, Y.V.; Ondar, E.E.; Ivanenkov, Y.A.; Evteev, S.A.; Vaneev, A.N.; Timoshenko, R.V.; Klyachko, N.L.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A.G. New Small-Molecule Glycoconjugates of Docetaxel and GalNAc for Targeted Delivery to Hepatocellular Carcinoma. Molecular Pharmaceutics, 2021, 18(1), 461–468. doi: 10.1021/acs.molpharmaceut.0c00980

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.