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YODi-1 (Oxazole Yellow Homodimer, also known as YOYO®-1) is a green fluorescent carbocyanine dimeric dye. YODi-1 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits over a thousand-fold fluorescence enhancement upon binding to dsDNA.
The bright fluorescence signal and low background make YODi-1 ideal for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in multicolor fluorescence labeling experiments. YODi-1 can also be used for the analysis of single molecules of DNA.
An amine derivative of ROX (Rhodamine X, Rhodamine 101) dye that is reactive toward electrophiles. It can also be used for enzymatic transamination labeling. Pure 6-isomer.
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General properties
Appearance:
orange solution
Molecular weight:
1270.66
CAS number:
143413-85-8
Molecular formula:
C49H58I4N6O2
Quality control:
NMR 1H and HPLC-MS (95+%)
Storage conditions:
24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.