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Ac4GalNAl (N-(4-pentynoyl)-galactosamine-tetraacylated)

Alkynes Click chemistry
貨號 數量 價格 交貨時間
4037-5mg 5 mg $129 現貨
4037-25mg 25 mg $240 現貨
4037-100mg 100 mg $630 現貨
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The tetraacetylated N-(4-pentynoyl)-galactosamine (Ac4GalNAl) is an alkyne-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.

Ac4GalNAl is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-acetylgalactosamine (GalNAc).

The resulting alkyne-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) click reaction with either fluorescent-labeled azides or biotin-azide.

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Ac4ManNAz (N-Azidoacetylmannosamine-tetraacylated)

An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.

Ac4GalNAz (N-Azidoacetylgalactosamine-tetraacylated)

An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.

Ac4ManNAl (N-(4-pentynoyl)-mannosamine-tetraacylated)

An alkyne-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.

General properties

Appearance: white solid
Molecular weight: 427.40
CAS number: 1658458-26-4
Molecular formula: C19H25NO10
IUPAC name: 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-(4-pentynoylamino)-α-D-galactopyranose
Solubility: DMSO, DMF, DCM, THF, chloroform
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
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產品規格
Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.
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