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Ac4ManNAz (N-Azidoacetylmannosamine-tetraacylated)

貨號 數量 價格 交貨時間
3159-5mg 5 mg
$129
現貨
3159-25mg 25 mg
$240
現貨
3159-100mg 100 mg
$630
現貨
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The tetraacetylated N-Azidoacetyl-mannosamine (Ac4ManNAz) is an azide-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.

Ac4ManNAz is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylmannosamine (ManNAc).

The resulting azide-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) or copper-free (SPAAC) click reaction with either fluorescent-labeled alkynes/cycloalkynes or biotin-alkyne.

The recommended concentration for cell labeling is 25-75 μM, and this concentration range may be a starting point for an individual experiment setup.

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General properties

Appearance: white solid
Molecular weight: 430.37
CAS number: 361154-30-5
Molecular formula: C16H22N4O10
Solubility: Soluble to 100 mM in DMSO
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
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