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ROX azide, 6-isomer

ROX (Rhodamine X, Rhodamine 101) Azides Click chemistry
貨號 數量 價格 交貨時間
A2230 1 mg $110 現貨
B2230 5 mg $165 現貨
C2230 10 mg $210 現貨
D2230 25 mg $285 現貨
E2230 50 mg $495 現貨
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ROX azide is an alkyne-reactive derivative of ROX (Rhodamine X, Rhodamine 101) dye. ROX is a red-emitting fluorophore possessing high brightness and fluorescence quantum yield. This reagent is a pure 6-isomer. It is used for labeling alkyne and cycloalkyne-containing biomolecules via copper-catalyzed and copper-free click chemistry reactions.

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General properties

Appearance: green powder
Molecular weight: 616.72
CAS number: 1422178-12-8
Molecular formula: C36H36N6O4
Solubility: good in polar organic solvents (DMF, DMSO, alcohols), low in water
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light.
MSDS: 下載
產品規格

Spectral properties

Excitation/absorption maximum, nm: 570
ε, L⋅mol−1⋅cm−1: 93000
Emission maximum, nm: 591
Fluorescence quantum yield: 1.0
CF260: 0.62
CF280: 0.49

產品引用

  1. Feltes, M.; Moores, S.; Gale, S.E.; Krishnan, K.; Mydock-McGrane, L.; Covey, D.F.; Ory, D.S.; Schaffer, J.E. Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking. Journal of Lipid Research, 2019, 60(3), 707–716. doi: 10.1194/jlr.D091470
  2. Okholm, A.; Kjems, J.; Astakhova, K. Fluorescence detection of natural RNA using rationally designed "clickable" oligonucleotide probes. RSC Advances, 2014, 4(86), 45653–45656. doi: 10.1039/c4ra07165d
  3. Liboska, R.; Ligasová, A.; Strunin, D.; Rosenberg, I.; Koberna, K. Most Anti-BrdU Antibodies React with 2'-Deoxy-5-Ethynyluridine ‒ The Method for the Effective Suppression of This Cross-Reactivity. PLoS ONE, 2012, 7(12), e51679. doi: 10.1371/journal.pone.0051679
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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