EdU（5-乙炔基-2'-脫氧尿苷）

Cell proliferation Alkynes Click chemistry

貨號	數量	價格	交貨時間
A0540	5 mg	–	現貨
10540	100 mg	$120	現貨
20540	250 mg	$195	現貨
30540	500 mg	$345	現貨
40540	1 g	$590	現貨
60540	5 g	請查詢	現貨

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EdU（5-乙炔基-2‘-脫氧尿苷）是一種核苷，是胸苷的類似物，帶有乙炔基。這種核苷可充當細胞 DNA 復製器的底物。 EdU 摻入後，含有乙炔基的 DNA可以通過點擊化學反應與各種疊氮化染料連接。熒光 DNA 可以通過顯微鏡檢測，或者通過 FACS 進行分細胞選。

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建議協議

Assaying Cell Proliferation and DNA Replication with Click Chemistry

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外观:
分子量:	252.22
CAS 编号:	61135-33-9
分子式:	C₁₁H₁₂N₂O₅
溶解度:
质量控制:
储存条件:
MSDS:	下載
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產品引用

Kim, R.; Allbritton, N.L. A Microphysiological System with an Anaerobic Air‐Liquid Interface and Functional Mucus Layer for Coculture of Intestinal Bacteria and Primary Human Colonic Epithelium. Advanced Materials Interfaces, 2024, 11(25), 2400093. doi: 10.1002/admi.202400093
Goedhart, J. Studentsourcing—Aggregating and reusing data from a practical cell biology course. PLOS Computational Biology, 2024, 20(2), e1011836. doi: 10.1371/journal.pcbi.1011836
Dopeso, H.; Rodrigues, P.; Cartón-García, F.; Macaya, I.; Bilic, J.; Anguita, E.; Jing, L.; Brotons, B.; Vivancos, N.; Beà, L.; Sánchez-Martín, M.; Landolfi, S.; Hernandez-Losa, J.; Ramon y Cajal, S.; Nieto, R.; Vicario, M.; Farre, R.; Schwartz Jr, S.; van Ijzendoorn, S.C.D.; Kobayashi, K.; Martinez-Barriocanal, Á.; Arango, D. RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis. iScience, 2024, 27(4), 109400. doi: 10.1016/j.isci.2024.109400
Alruwaili, M.M.; Zonneville, J.; Naranjo, M.N.; Serio, H.; Melendy, T.; Straubinger, R.M.; Gillard, B.; Foster, B.A.; Rajan, P.; Attwood, K.; Chatley, S.; Iyer, R.; Fountzilas, C.; Bakin, A.V. A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers. Cell Reports Medicine, 2024, 5(3), 101434. doi: 10.1016/j.xcrm.2024.101434