Cyanine5 羧酸 (Cyanine5 carboxylic acid)

Carboxylic acids Cyanine5

貨號	數量	價格	交貨時間
13090	1 mg	$110	現貨
23090	5 mg	$210	現貨
43090	25 mg	$410	現貨
53090	50 mg	$695	現貨
63090	100 mg	$1190	現貨

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非活化羧酸，Cy5® 游離羧酸的類似物。含有 Cyanine5 螢光團。

該染料的水溶性不好，但可以溶解在水與有機相（DMF、DMSO、醇）的混合液中，以獲得材料的有用濃度。可提供其水溶版。

該分子可被視為非反應性染料，用於對照樣品和儀器校准。對於與胺和蛋白質標記的偶聯，請考慮使用Cyanine5 NHS 酯或水溶性sulfo-Cyanine5 NHS 酯。

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DMSO (dimethyl sulfoxide), labeling grade

Pure dimethyl sulfoxide (DMSO) solvent with quality optimized for bioconjugation reactions.

氨基-11-dUTP

Amino-11-dUTP 是一種用於修飾 DNA 的三磷酸鹽。

sulfo-Cyanine5.5 maleimide

sulfo-Cyanine5.5 is a water-soluble far-red emitting dye. This is a thiol-reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

外观:	深金固體
分子量:	519.12
CAS 编号:	1032678-07-1 (chloride), 195867-59-5 (inner salt), 766503-38-2 (without anion)
分子式:	C₃₂H₃₉ClN₂O₂
IUPAC 名称:	3H-Indolium, 2-[5-[1-(5-carboxypentyl)-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1,3,3-trimethyl-, chloride
溶解度:	溶於有機溶劑（DMF、DMSO、二氯甲烷），極難溶於水（0.25 mM，130 mg/L）
质量控制:	NMR ¹H, HPLC-MS (95%)
储存条件:
MSDS:	下載
	產品規格

激发/吸收极大值，纳米:	646
ε, 摩尔吸光系数，cm⁻¹:	250000
发射极大值，纳米:	662
荧光量子产率:	0.2
CF₂₆₀:	0.03
CF₂₈₀:	0.04

產品引用

Tchatchiashvilli, T.; Duering, H.; Mueller-Boetticher, L.; Grune, C.; Fischer, D.; Pletz, M.W.; Makarewicz, O. PEG-PLGA nanoparticles deposited in Pseudomonas aeruginosa and Burkolderia cenocepacia. Journal of Pharmaceutical Analysis, 2024. doi: 10.1016/j.jpha.2024.01.007
Yao, P.; Wang, X.; Wang, Q.; Dai, Q.; Peng, Y.; Yuan, Q.; Mou, N.; Lv, S.; Weng, B.; Wang, Y.; Sun, F. Cyclic RGD-Functionalized PH/ROS Dual-Responsive Nanoparticle for Targeted Breast Cancer Therapy. Pharmaceutics, 2023, 15(7), 1827. doi: 10.3390/pharmaceutics15071827
Lu, Y.; Zhou, J.; Wang, Q.; Cai, J.; Yu, B.; Dai, Q.; Bao, Y.; Chen, R.; Zhang, Z.; Zhang, D.; Hou, T. Glucocorticoid-Loaded PH/ROS Dual-Responsive Nanoparticles Alleviate Joint Destruction by Downregulating the NF-ΚB Signaling Pathway. Acta Biomaterialia, 2023, 164, 458–473. doi: 10.1016/j.actbio.2023.04.012
Rezaei, S.; de Araújo Júnior, R. F.; da Silva, I. L. G.; Schomann, T.; Eich, C.; Cruz, L. J. Erythrocyte−cancer Hybrid Membrane-Coated Reduction-Sensitive Nanoparticles for Enhancing Chemotherapy Efficacy in Breast Cancer. Biomaterials Advances, 2023, 151, 213456. doi: 10.1016/j.bioadv.2023.213456