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sulfo-Cyanine5.5 azide

Azides sulfo-Cyanine5.5 Click chemistry
貨號 數量 價格 交貨時間
A7330 1 mg $110 現貨
B7330 5 mg $325 現貨
C7330 10 mg $470 現貨
D7330 25 mg $850 現貨
E7330 50 mg $1490 現貨
F7330 100 mg $2590 現貨
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sulfo-Cyanine5.5 is a water-soluble, hydrophilic fluorophore with emission in the far-red area of the spectrum, an analog of Cy5.5®. Like other cyanine dyes, sulfo-Cyanine5.5 has an outstanding molar extinction coefficient, giving rise to its bright fluorescence. The molecule contains four sulfo groups that provide hydrophilicity and negative charge to the fluorophore — this minimizes non-specific binding.

The azide group of Sulfo-Cyanine5.5 azide can be conjugated with terminal alkynes in the presence of copper(I) catalyst or with cycloalkynes in copper-free strain-promoted reaction.

The reagent possesses high hydrophilicity and is recommended for labeling biomolecules in an aqueous environment.

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BDP 650/665 azide

BDP 650/665 is a red-emitting borondipyrromethene dye. This azide derivative can be conjugated with alkynes and cycloalkynes.

菁染料5胺 (Cyanine5 amine)

菁染料5胺官能化染料，用於與活化酯和環氧化物偶聯。
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AF 647 azide

Bright and photostable azide AF 647 for labeling alkyne-containing biomolecules and fluorescent visualization of biological objects.

General properties

Appearance: dark colored solid
Mass spec M+ increment: 984.2
Molecular weight: 1099.41
CAS number: 2382994-65-0
Molecular formula: C43H45K3N6O13S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
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產品規格

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

產品引用

  1. Sajeesh, S.; Camardo, A.; Dahal, S.; Ramamurthi, A. Surface-Functionalized Stem Cell-Derived Extracellular Vesicles for Vascular Elastic Matrix Regenerative Repair. Molecular Pharmaceutics, 2023, 20(6), 2801-2813. doi: 10.1021/acs.molpharmaceut.2c00769
  2. Erel-Akbaba, G.; Carvalho, L.A.; Tian, T.; Zinter, M.; Akbaba, H.; Obeid, P.J.; Chiocca, E.A.; Weissleder, R.; Kantarci, A.G.; Tannous, B.A. Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy. ACS Nano, 2019, 13(4), 4028–4040. doi: 10.1021/acsnano.8b08177
  3. Gu, W.; Bobrin, V.A.; Chen, S.-P.R.; Wang, Z.; Schoning, J.P.; Gu, Y.; Chen, W.; Chen, M.; Jia, Z.; Monteiro, M.J. Biodistribution of PNIPAM-Coated Nanostructures Synthesized by the TDMT Method. Biomacromolecules, 2019, 20(2), 625–634. doi: 10.1021/acs.biomac.8b01196
Cy® is a trademark of GE Healthcare.
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