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VdU (5-Vinyl-2'-deoxyuridine)

Cell proliferation Copper-free click chemistry

貨號	數量	價格	交貨時間
B2540	5 mg	–	現貨
D2540	25 mg	$225	現貨
F2540	100 mg	$785	現貨

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VdU (5-Vinyl-2’-deoxyuridine) is a synthetic analog of thymidine that can be used to study de novo DNA synthesis and cell proliferation. It is a potential replacement for BrdU (5-Bromo-2’-deoxyuridine) or EdU (5-Ethynyl-2’-deoxyuridine).

VdU incorporates into replicating DNA during the S-phase of the cell cycle instead of natural thymidine. The resulting vinyl-functionalized DNA can be detected by introducing either a biotin or fluorescent dye group via a cooper-free alkene-tetrazine reaction (also known as Inverse electron demand Diels-Alder ligation or IEDDA) and used for subsequent DNA purification or cell imaging tasks.

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VU (5-Vinyl-uridine)

Uridine derivative with a terminal alkene group for monitoring and investigating cell RNA transcription.

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Water soluble sulfo-Cyanine3 dye tetrazine derivative for TCO ligation labeling with trans-cyclooctenes.

General properties

Appearance:	yellowish solid
Molecular weight:	254.24
CAS number:	55520-67-7
Molecular formula:	C₁₁H₁₄N₂O₅
Solubility:	in DMSO
Quality control:	NMR ¹H and HPLC-MS (95+%)
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	下載
	產品規格