AF 568 DBCO
| 貨號 | 數量 | 價格 | 交貨時間 | 購買此產品 |
|---|---|---|---|---|
| 1158F0 | 1 mg |
$199.90
|
現貨 | |
| 2158F0 | 5 mg |
$659.90
|
現貨 | |
| 4158F0 | 25 mg |
$2099.00
|
現貨 | |
| 5158F0 | 50 mg |
$2799.00
|
現貨 | |
| 6158F0 | 100 mg |
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|
現貨 |
Dibenzocyclooctyne (DBCO, DBCO, ADIBO) is one of the most reactive cycloalkynes for copper-free click reaction (SPAAC, strain-promoted azide-alkyne cycloaddition). The rate of interaction of DBCO with azides is significantly higher than that of other cyclooctynes, as well as Cu-catalyzed click reaction (CuAAC). Unlike other cyclooctynes, DBCO does not interact with tetrazines, which makes it possible to use it in bioorthogonal reactions together with trans-cyclooctenes and tetrazines.
AF 568 is a bright, photostable, and hydrophilic fluorophore that emits in the orange channel. The absorption maximum is 572 nm. The emission maximum is 598 nm.
AF 568 DBCO allows fluorescent labeling of azide-containing biomolecules inside living cells and whole organisms without the negative effect of copper ions on them, and inanimate samples.
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General properties
| Appearance: | dark violet solid |
| Molecular weight: | 1197.53 |
| Molecular formula: | C66H80N6O11S2 |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light. |
| MSDS: | 下載 |
| 產品規格 |
Spectral properties
| Excitation/absorption maximum, nm: | 572 |
| ε, L⋅mol−1⋅cm−1: | 94238 |
| Emission maximum, nm: | 598 |
| Fluorescence quantum yield: | 0.912 |
產品引用
- Kofoed, C.; Erkalo, G.; Tay, N. E. S.; Ye, X.; Lin, Y.; Muir, T. W. Programmable Protein Ligation on Cell Surfaces. Nature, 2025, 645(8081), 793–800. doi: 10.1038/s41586-025-09287-2
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