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Ac4GlcNAz (N-Azidoacetylglucosamine-tetraacylated)

貨號 數量 價格 交貨時間
3662-5mg 5 mg $129 現貨
3662-25mg 25 mg $240 現貨
3662-100mg 100 mg $630 現貨
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The tetraacetylated N-Azidoacetyl-glucosamine (Ac4GlcNAz) is an azide-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.

Ac4GlcNAz is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylglucosamine (GlcNAc).

The resulting azide-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) or copper-free (SPAAC) click reaction with either fluorescent-labeled alkynes/cycloalkynes or biotin-alkyne.

The recommended concentration for cell labeling is 25-75 μM, and this concentration range may be a starting point for an individual experiment setup.

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AmdU (5-Azidomethyl-2'-deoxyuridine)

Azidomethyldeoxyuridine (AmdU) is an azide-contained nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain-promoted click reaction.

DAPI, blue fluorescent nucleic acid stain

DAPI (4′,6-diamidino-2-phenylindole) is a blue-emitting fluorescent DNA dye used for chromosome staining and as a nuclear counterstain in fluorescence microscopy and flow cytometry.

Ac4GalNAz (N-Azidoacetylgalactosamine-tetraacylated)

An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.

General properties

Appearance: white solid
Molecular weight: 430.37
CAS number: 98924-81-3
Molecular formula: C16H22N4O10
Solubility: DMSO, DMF, DCM, THF, Chloroform
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
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