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TAMRA maleimide, 5-isomer

TAMRA 馬來酰亞胺

貨號	數量	價格	交貨時間
17180	1 mg	$110	現貨
27180	5 mg	$210	現貨
47180	25 mg	$410	現貨
57180	50 mg	$695	現貨
67180	100 mg	$1190	現貨

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TAMRA is a well-known rhodamine dye. It is available as two isomers, 5-, and 6-, which have almost identical properties, but need to be separated. This is a thiol-reactive maleimide derivative of 5-TAMRA.

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建議協議

Maleimide Labeling of Proteins and Other Thiolated Biomolecules

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TAMRA maleimide, 6-isomer

TAMRA is a well-known xanthene dye of the rhodamine series. This reagent is a thiol-reactive maleimide for the labeling of SH groups in proteins and peptides. Pure 6-isomer.

General properties

Appearance:	red powder
Mass spec M+ increment:	552.2
Molecular weight:	552.58
Molecular formula:	C₃₁H₂₈N₄O₆
IUPAC name:	1-[2-({3',6'-Bis(dimethylamino)-3-oxospiro[isobenzofuran-1,9'-xanthen]-5-yl}carbonylamino)ethyl]-1H-pyrrole-2,5-dione
Solubility:	good in DMF, DMSO
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	下載
	產品規格

Spectral properties

Excitation/absorption maximum, nm:	541
ε, L⋅mol⁻¹⋅cm⁻¹:	84000
Emission maximum, nm:	567
Fluorescence quantum yield:	0.1
CF₂₆₀:	0.32
CF₂₈₀:	0.19

產品引用

Han, X.; Lu, X.; Li, P.H.; Wang, S.; Schalek, R.; Meirovitch, Y.; Lin, Z.; Adhinarta, J.; Murray, K.D.; MacNiven, L.M.; Berger, D.R.; Wu, Y.; Fang, T.; Meral, E.S.; Asraf, S.; Ploegh, H.; Pfister, H.; Wei, D.; Jain, V.; Trimmer, J.S.; Lichtman, J.W. Multiplexed volumetric CLEM enabled by scFvs provides insights into the cytology of cerebellar cortex. Nature Communications, 2024, 15, 6648. doi: 10.1038/s41467-024-50411-z

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.