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sulfo-Cyanine5.5 maleimide

磺基-花菁5.5 馬來酰亞胺

貨號	數量	價格	交貨時間
17380	1 mg	$125	現貨
27380	5 mg	$325	現貨
47380	25 mg	$790	現貨
57380	50 mg	$1490	現貨
67380	100 mg	$1990	現貨

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sulfo-Cyanine5.5 dye is a water-soluble far-red to NIR emitting dye that is very hydrophilic due to the presence of four sulfo groups. sulfo-Cyanine5.5 derivatives exhibit high water solubility. The dye is perfect for labeling sensitive proteins, nanoparticles, and highly hydrophilic biopolymers.

This maleimide is a thiol-reactive dye that selectively labels cysteine residues. Disulfide bonds of native proteins should be reduced with an appropriate reducing agent, such as TCEP, according to our recommended protocol.

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建議協議

Maleimide Labeling of Proteins and Other Thiolated Biomolecules

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General properties

Appearance:	dark colored solid
Mass spec M+ increment:	1024.2
Molecular weight:	1139.43
CAS number:	2183440-58-4 (potassium salt); 2183440-57-3 (inner salt)
Molecular formula:	C₄₆H₄₅K₃N₄O₁₅S₄
Solubility:	good in water, DMSO, DMF
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	下載
	產品規格

Spectral properties

Excitation/absorption maximum, nm:	673
ε, L⋅mol⁻¹⋅cm⁻¹:	211000
Emission maximum, nm:	691
Fluorescence quantum yield:	0.21
CF₂₆₀:	0.09
CF₂₈₀:	0.11

產品引用

Xiang, L.; Henderson, M. I.; Drennan, S.; Sabuncu, S.; Fischer, J. M.; Yildirim, A. Peptide Amphiphile–Nanoparticle Assemblies for Mechano-Chemo Combination Therapy. Nano Lett, 2025. doi: 10.1021/acs.nanolett.5c01112
Bayon, J.L.; Shih, C.; Craig, S.L.; Steinmetz, N.F. A simple swell-and-click method for the covalent attachment of virus-like particles to polymer hydrogels. Materials Today Chemistry, 2024, 38, 102100. doi: 10.1016/j.mtchem.2024.102100
Sabuncu, S.; Montoya Mira, J.; Quentel, A.; Gomes, M. M.; Civitci, F.; Fischer, J. M.; Yildirim, A. Protein-Coated Biodegradable Gas-Stabilizing Nanoparticles for Cancer Therapy and Diagnosis Using Focused Ultrasound. Advanced Materials Interfaces, 2023, 10(2), 2201543. doi: 10.1002/admi.202201543
Das, S.K.; Huynh, M.T.; Lee, T.-H. Spontaneous histone exchange between nucleosomes. The Journal of Biological Chemistry, 2023, 299(8), 105037. doi: 10.1016/j.jbc.2023.105037