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sulfo-Cyanine5.5 amine

貨號	數量	價格	交貨時間
173C0	1 mg	$125	現貨
273C0	5 mg	$285	現貨
473C0	25 mg	$680	現貨
573C0	50 mg	$1260	現貨
673C0	100 mg	$1990	現貨

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sulfo-Cyanine5.5 is a water-soluble cyanine dye for far red / NIR applications such as in vivo imaging. The dye possesses four sulfonate groups, rendering it highly hydrophilic and water-soluble. As well as other cyanines, sulfo-Cyanine5.5 has an outstanding extinction coefficient that makes it a bright fluorescent label for the far-red region.

This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. The aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc.) and used in enzymatic transamination labeling.

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ChemDraw 格式下載

General properties

Appearance:	dark blue solid
Molecular weight:	1077.41
CAS number:	2183440-46-0
Molecular formula:	C₄₆H₅₄K₂N₄O₁₃S₄
IUPAC name:	(E)-4-[(2E,4E)-5-{5-[6-(6-Aminohexylamino)-6-oxohexyl]-3,3-dimethyl-10,12-bis(oxysulfonyl)-5-azatricyclo[7.4.0.02,6]trideca-1,4,6,8,10,12-hexaen-4-yl}-2,4-pentadienylidene]-3,3-dimethyl-5-methyl-5-azatricyclo[7.4.0.02,6]trideca-1,6,8,10,12-pentaene-10,12-disulfonic acid dipotassium salt
Solubility:	good in water, DMF, DMSO
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	下載
	產品規格

Spectral properties

Excitation/absorption maximum, nm:	673
ε, L⋅mol⁻¹⋅cm⁻¹:	211000
Emission maximum, nm:	691
Fluorescence quantum yield:	0.21
CF₂₆₀:	0.09
CF₂₈₀:	0.11

產品引用

Gao, W.; He, J.; Chen, L.; Meng, X.; Ma, Y.; Cheng, L.; Tu, K.; Gao, X.; Liu, C.; Zhang, M.; Fan, K.; Pang, D.-W.; Yan, X. Deciphering the Catalytic Mechanism of Superoxide Dismutase Activity of Carbon Dot Nanozyme. Nature Communications, 2023, 14(1), 160. doi: 10.1038/s41467-023-35828-2
Shevchuk, A. I.; Svinko, V. O.; Smirnov, A. N.; Solovyeva, E. V. SERS Study of Cyanine Dyes: Optimization of Metal Core and Molecular Label Choice for Plasmonic Nanotags. Dyes and Pigments, 2023, 216, 111329. doi: 10.1016/j.dyepig.2023.111329.
Wang, D.; Li, Y.; Deng, X.; Torre, M.; Zhang, Z.; Li, X.; Zhang, W.; Cullion, K.; Kohane, D. S.; Weldon, C. B. An Aptamer-Based Depot System for Sustained Release of Small Molecule Therapeutics. Nature Communications, 2023, 14(1), 2444. doi: 10.1038/s41467-023-37002-0
Zha, H.; Xu, Z.; Xu, X.; Lu, X.; Shi, P.; Xiao, Y.; Tsai, H.-I.; Su, D.; Cheng, F.; Cheng, X.; Chen, H. PD-1 Cellular Nanovesicles Carrying Gemcitabine to Inhibit the Proliferation of Triple Negative Breast Cancer Cell. Pharmaceutics, 2022, 14(6), 1263. doi: 10.3390/pharmaceutics14061263