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sulfo-Cyanine5 DBCO

環炔烴無銅點擊化學磺基-花菁5

貨號	數量	價格	交貨時間
133F0	1 mg	$125	現貨
233F0	5 mg	$325	現貨
433F0	25 mg	$850	現貨
533F0	50 mg	$1490	現貨
633F0	100 mg	$1990	現貨

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Copper-free click chemistry reaction between strained cycloalkynes (cyclooctynes) and azides is a very fast and robust reaction. It can be used for fast labeling with fluorescent dyes. This reagent is a derivative of water-soluble sulfo-Cyanine5 dye, which emits in a red channel. It is useful for the labeling of biomolecules in aqueous media.

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FAM 馬來酰亞胺，6-異構體 (FAM maleimide, 6-isomer)

熒光素 (FAM) 馬來酰亞胺是一種由純 6-FAM 異構體衍生而來的巰基活性染料。熒光素是一種明亮的染料，與各種熒光測量儀器兼容。

DBCO-amine trifluoroacetate

Bifunctional linker containing dibenzocyclooctyne (DBCO, ADIBO) for strain-promoted copper-free click reaction (SPAAC) and free amine for the coupling with various electrophilic compounds like activated esters and epoxides.

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Cyanine3 DBCO

Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper-free click chemistry.

General properties

Appearance:	dark colored solid
Molecular weight:	981.27
Molecular formula:	C₅₃H₅₇N₄KO₈S₂
Solubility:	good in water, DMF, DMSO
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	下載
	產品規格

Spectral properties

Excitation/absorption maximum, nm:	646
ε, L⋅mol⁻¹⋅cm⁻¹:	271000
Emission maximum, nm:	662
Fluorescence quantum yield:	0.28

產品引用

Hebels, E. R.; Bindt, F.; Walther, J.; van Geijn, M.; Weterings, J.; Hu, Q.; Colombo, C.; Liskamp, R.; Rijcken, C.; Hennink, W. E.; Vermonden, T. Orthogonal Covalent Entrapment of Cargo into Biodegradable Polymeric Micelles via Native Chemical Ligation. Biomacromolecules, 2023, 24(10), 4385–4396. doi: 10.1021/acs.biomac.2c00865
Sapozhnikova, K. A.; Gulyak, E. L.; Misyurin, V. A.; Simonova, M. A.; Ryabukhina, E. V.; Alexeeva, A. V.; Tikhonova, N. A.; Lyzhko, N. A.; Popova, G. P.; Misyurin, A. V.; Ustinov, A. V.; Korshun, V. A.; Alferova, V. A.; Ryazantsev, D. Y.; Brylev, V. A. Branched Linkers for Site-Specific Fluorescent Labeling of Antibodies. Molecules, 2023, 28(1), 425. doi: 10.3390/molecules28010425
Williams, C.; Dong, K. C.; Arkinson, C.; Martin, A. The Ufd1 Cofactor Determines the Linkage Specificity of Polyubiquitin Chain Engagement by the AAA+ ATPase Cdc48. Molecular Cell, 2023, 83(5), 759-769.e7. doi: 10.1016/j.molcel.2023.01.016
Pontes, A.P.; van der Wal, S.; Ranamalla, S.R.; Roelofs, K.; Tomuta, I.; Creemers, L.B.; Rip, J. Cell uptake and intracellular trafficking of bioreducible poly(amidoamine) nanoparticles for efficient mRNA translation in chondrocytes. Frontiers in Bioengineering and Biotechnology, 2023, 11, 1290871. doi: 10.3389/fbioe.2023.1290871

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This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.