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FAM DBCO, 6-isomer

FAM（螢光素）環炔烴 Copper-free click chemistry

貨號	數量	價格	交貨時間
151F0	1 mg	$110	現貨
251F0	5 mg	$160	現貨
451F0	25 mg	$260	現貨
551F0	50 mg	$370	現貨
651F0	100 mg	$525	現貨

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Fluorescein (FAM) is one of the oldest yet well-known fluorescent dyes. This derivative of FAM contains the cyclooctyne group (dibenzocyclooctyne, DBCO or ADIBO). Pure 6-isomer. DBCO reacts quickly and efficiently with azides by simply mixing the components without the need for a copper catalyst (so-called sterically promoted cycloaddition reaction or SPAAC).

FAM DBCO can be used for the labeling of proteins, peptides, nucleic acids, and other molecules containing azide groups. Fluorescein can be detected using a variety of different instruments.

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BDP® 630/650 炔烴 (BDP® 630/650 alkyne)

用於銅催化點擊化學的炔烴染料，含有用於紅色通道的硼二吡咯亞甲基螢光團 BDP 630/650。

花青3胺 (Cyanine3 amine)

Cyanine3 是一種帶有游離氨基的螢光團（氨基染料）。它可以與 NHS 酯、羧基（活化後）和環氧化物共軛。

磺基-Cyanine7.5疊氮化物 (sulfo-Cyanine7.5 azide)

sulfo-Cyanine7.5 是一種非常親水的水溶性近紅外染料。該染料的吸收和發射光譜與吲哚花菁綠（ICG）相似，但sulfo -Cyanine7.5具有更高的螢光量子產率。該染料是近紅外體內成像的絕佳選擇。是一種用於點擊化學的疊氮化物。

General properties

Appearance:	orange solid
Molecular weight:	676.71
Molecular formula:	C₄₂H₃₂N₂O₇
Solubility:	good in DMF, DMSO
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	下載
	產品規格

Spectral properties

Excitation/absorption maximum, nm:	492
ε, L⋅mol⁻¹⋅cm⁻¹:	74000
Emission maximum, nm:	517
Fluorescence quantum yield:	0.93

產品引用

Kaneda, K.; Takeuchi, Y.; Yamanaka, K.; Hasebe, F.; Maruyama, C.; Hamano, Y. Cell-penetrating activity of a short-chain ε-poly-l-α-lysine. Journal of Bioscience and Bioengineering, 2024, 138(3), 249-253. doi: 10.1016/j.jbiosc.2024.06.006
Wu, F.; Ren, Y.; Lv, W.; Liu, X.; Wang, X.; Wang, C.; Cao, Z.; Liu, J.; Wei, J.; Pang, Y. Generating dual structurally and functionally skin-mimicking hydrogels by crosslinking cell-membrane compartments. Nature Communications, 2024, 15(1), 802. doi: 10.1038/s41467-024-45006-7
Jaiswal, M.; Tran, T. T.; Guo, J.; Zhou, M.; Kundu, S.; Guo, Z.; Fanucci, G. E. Spin-Labeling Insights into How Chemical Fixation Impacts Glycan Organization on Cells. Appl Magn Reson, 2023. doi: 10.1007/s00723-023-01624-w
Sapozhnikova, K. A.; Gulyak, E. L.; Misyurin, V. A.; Simonova, M. A.; Ryabukhina, E. V.; Alexeeva, A. V.; Tikhonova, N. A.; Lyzhko, N. A.; Popova, G. P.; Misyurin, A. V.; Ustinov, A. V.; Korshun, V. A.; Alferova, V. A.; Ryazantsev, D. Y.; Brylev, V. A. Branched Linkers for Site-Specific Fluorescent Labeling of Antibodies. Molecules, 2023, 28(1), 425. doi: 10.3390/molecules28010425

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Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.