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sulfo-Cyanine5 alkyne

Alkynes sulfo-Cyanine5 Click chemistry
貨號 數量 價格 交貨時間
A33B0 1 mg $125 現貨
B33B0 5 mg $290 現貨
C33B0 10 mg $470 現貨
D33B0 25 mg $850 現貨
E33B0 50 mg $1490 現貨
F33B0 100 mg $1990 現貨
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Water soluble reagent with alkyne group for click chemistry. Sulfo-Cyanine5 is a sulfonated dye with high hydrophilicity and aqueous solubility, exceptionally high extinction coefficient, good quantum yield, and compatibility with many instruments.

This reagent is recommended for the conjugation with proteins, nanoparticles, and other applications where hydrophilicity is important.

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AF 488 疊氮化物

AF 488 疊氮化物是一種發射在綠色光譜範圍內的熒光團。它與炔烴在銅催化的條件下發生環加成反應。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.
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TAMRA alkyne, 5-isomer

Alkyne derivative of TAMRA dye, pure 5-isomer for сopper-catalyzed сlick chemistry.

General properties

Appearance: dark blue solid
Molecular weight: 717.94
CAS number: 1617572-09-4 (inner salt); 1617497-19-4 (sodium salt)
Molecular formula: C35H40N3KO7S2
Solubility: very high in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
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產品規格

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

產品引用

  1. Yoshikawa, A. M.; Rangel, A. E.; Zheng, L.; Wan, L.; Hein, L. A.; Hariri, A. A.; Eisenstein, M.; Soh, H. T. A Massively Parallel Screening Platform for Converting Aptamers into Molecular Switches. Nat Commun, 2023, 14(1), 2336. doi: 10.1038/s41467-023-38105-4
  2. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Scientific Reports, 2021, 11(1), 12229. doi: 10.1038/s41598-021-91612-6.
  3. Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a "multiple gear" regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
  4. Guarin, M.; Ny, A.; De Croze, N.; Maes, J.; Léonard, M.; Annaert, P.; de Witte, P. A. M. Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis. Pharmaceuticals, 2021, 14(6), 576. doi: 10.3390/ph14060576
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Cy® is a trademark of GE Healthcare.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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