sulfo-Cyanine3 hydrazide
貨號 | 數量 | 價格 | 交貨時間 | 購買此產品 |
---|---|---|---|---|
11370 | 1 mg | $125 | 現貨 | |
21370 | 5 mg | $325 | 現貨 | |
41370 | 25 mg | $850 | 現貨 | |
51370 | 50 mg | $1490 | 現貨 | |
61370 | 100 mg | $1990 | 現貨 |
sulfo-Cyanine3 is a sulfated derivative of Cyanine3 dye, well soluble in water because of two negatively charged sulfo groups in its structure. By its spectral characteristics, this yellow-orange fluorescent dye is an analog of Cy™3.
Hydrazides efficiently react with aldehydes and ketones resulting in hydrazones, so this compound can be used for conjugation with carbonyl derivatives of biomolecules.
The reaction runs in aqueous conditions, which is important when working with antibodies and proteins. Cys-diol groups in sugars in glycosylated proteins and antibodies can be oxidized into dialdehydes, and cysteine in proteins can be converted with enzymes to formyl glycerol (i. e. reactive groups for conjugation with sulfo-Cyanine3 hydrazide). Carboxyl groups of aspartic and glutamic acids in proteins and peptides can be also conjugated with sulfo-Cyanine3 hydrazide in the presence of activating agents: carbodiimide (EDAC) or methyl morpholine (DMTMM) derivatives.
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AF 488 酰肼 (AF 488 hydrazide)
AF 488 酰肼是一種羰基活性染料,可與醛和酮結合。sulfo-Cyanine5.5 amine
sulfo-Cyanine5.5 is a far-red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. This is an amine derivative that is reactive toward electrophiles. It can also be used for enzymatic transamination labeling.AF 488 NHS 酯 (AF 488 NHS ester)
AF 488 NHS 酯,一種明亮、光穩定、親水性的綠色通道熒光染料。General properties
Appearance: | dark red solid |
Molecular weight: | 630.78 |
CAS number: | 2144762-62-7 |
Molecular formula: | C30H38N4O7S2 |
IUPAC name: | 3H-Indolium, 2-[3-[1-(6-hydrazinyl-6-oxohexyl)-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1-propen-1-yl]-1,3,3-trimethyl-5-sulfo-, inner salt |
Solubility: | soluble in water, DMF, DMSO |
Quality control: | NMR 1H, HPLC-MS (90%) |
Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. |
MSDS: | 下載 |
產品規格 |
Spectral properties
Excitation/absorption maximum, nm: | 548 |
ε, L⋅mol−1⋅cm−1: | 162000 |
Emission maximum, nm: | 563 |
Fluorescence quantum yield: | 0.1 |
CF260: | 0.03 |
CF280: | 0.06 |