Neuro-DiO, lipophilic tracer
| 貨號 | 數量 | 價格 | 交貨時間 | 購買此產品 |
|---|---|---|---|---|
| 4175-1mg | 1 mg | – | 現貨 | |
| 4175-25mg | 25 mg | $210 | 現貨 |
Neuro-DiO is a green fluorescent, lipophilic carbocyanine dye with excitation max. at 497 nm, and emission max. at 514 nm. Neuro-DiO is an analog of DiO, a widely used anterograde and retrograde neuronal tracer for living and fixed tissues and cells. In contrast to DiO, Neuro-DiO has been specifically designed to improve solubility in membranes and prevent the formation of nonfluorescent aggregates, which tend to decrease the dye diffusion rate.
Neuro-DiO uniformly labels neurons via diffusion in the plasma membrane. In intact tissue, the dye does not transfer from labeled to unlabeled cells, but some transfer may occur when the membrane is disrupted, for example, after sectioning.
Neuro-DiO can be used together with other lipophilic tracers (DiI, DiD, DiR, etc.) in dual-color and multi-color studies.
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DiO，親脂性示蹤劑 (DiO, lipophilic tracer)
用於膜標記和細胞示蹤的綠色螢光親脂染料。6-Carboxy-H2DCFDA (6-carboxy-2',7'-dichlorodihydrofluorescein)
A reagent for detecting reactive oxygen species (ROS) in living cells. This carboxylated H2DCFDA analog has two additional negative charges that impede its leakage out of the cell.(5,6)-FAM diacetate NHS ester
Amine-reactive fluorescein (FAM) derivative, a mixture of 5- and 6-isomers. The reagent becomes brightly green fluorescent once it is hydrolyzed while diffusing into cells. A fluorescent tracer.General properties
| Appearance: | orange oil |
| Molecular weight: | 1043.56 |
| Molecular formula: | C62H101F3N2O5S |
| Solubility: | DMF, DMSO, ethanol |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | 下載 |
| 產品規格 |
Spectral properties
| Excitation/absorption maximum, nm: | 497 |
| Emission maximum, nm: | 514 |
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