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LumiCell CDr20 Microglia Stain

貨號 數量 價格 交貨時間
3570-50ug 50 ug $50 現貨
3570-500ug 500 ug $350 現貨
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CDr20 (Cell Designation red 20) is a high-performance fluorogenic chemical probe for labeling microglia in both cell cultures and live brains. CDr20 is a substrate of microglia-specific UDP-glucuronosyltransferase Ugt1a7c. The glucuronidation of CDr20 by Ugt1a7c produces bright red fluorescence in microglial cells coinciding with the expression of markers P2ry12, Csf1r, Cx3cr1, and Iba-1 [1].

CDr20 could be a valuable tool for identifying and visualizing microglia in neural disorder studies both in vitro and in vivo and for CDr20-based fluorescent-activated microglial cell sorting (FACS).

[1] Kim B. et al. Visualizing Microglia with a Fluorescence Turn-On Ugt1a7c Substrate. Angew. Chem. Int. Ed. Engl. 2019. 58(24). 7972-7976.

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General properties

Appearance: greenish black crystals
Molecular weight: 354.17
CAS number: 1201643-01-7
Molecular formula: C19H17BF2N2O2
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: 下載
產品規格

Spectral properties

Excitation/absorption maximum, nm: 562
ε, L⋅mol−1⋅cm−1: 97500
Emission maximum, nm: 581
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