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Cyanine7 DBCO

Cycloalkynes Cyanine7 Copper-free click chemistry Near infrared (NIR) imaging
貨號 數量 價格 交貨時間
A50F0 1 mg $125 現貨
B50F0 5 mg $260 現貨
C50F0 10 mg $325 現貨
D50F0 25 mg $510 現貨
E50F0 50 mg $895 現貨
F50F0 100 mg $1490 現貨
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Cyanine7 DBCO is a NIR fluorescent dye with cycloalkyne moiety for the conjugation with azides by means of copper-free, strain-promoted alkyne-azide cycloaddition (SPAAC).

Azodibenzocyclooctyne (DBCO or ADIBO) fragment is a stable but active cycloalkyne that reacts very rapidly with azides.

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DMSO (dimethyl sulfoxide), labeling grade

Pure dimethyl sulfoxide (DMSO) solvent with quality optimized for bioconjugation reactions.

Cyanine7胺

Cy7 胺是一種近紅外染料，具有游離的胺基，可與活化酯和其他反應性分子結合。
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BDP® 558/568 azide

BDP 558/568 is a borondipyrromethene fluorophore with absorption and emission spectra close to Cyanine3. This is an azide derivative for сlick chemistry.

General properties

Appearance: dark green solid
Mass spec M+ increment: 849.5
Molecular weight: 885.62
CAS number: 2692677-77-1
Molecular formula: C58H65N4ClO2
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: 下載
產品規格

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3

產品引用

  1. Park, J. S.; Lim, Y. G.; Park, K. Novel Bidentate β-Glutamic Acid-Based Bone-Targeting Agents for in Vivo Bone Imaging. Journal of Industrial and Engineering Chemistry, 2022, 110, 471–478. doi: 10.1016/j.jiec.2022.03.021
  2. Jäger, E.; Humajová, J.; Dölen, Y.; Kučka, J.; Jäger, A.; Konefał, R.; Pankrác, J.; Pavlova, E.; Heizer, T.; Šefc, L.; Hrubý, M.; Figdor, C. G.; Verdoes, M. Enhanced Antitumor Efficacy through an “AND Gate” Reactive Oxygen-Species-Dependent PH-Responsive Nanomedicine Approach. Advanced Healthcare Materials, 2021, 10(13), 2100304. doi: 10.1002/adhm.202100304
  3. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
  4. Alberg, I.; Kramer, S.; Schinnerer, M.; Hu, Q.; Seidl, C.; Leps, C.; Drude, N.; Möckel, D.; Rijcken, C.; Lammers, T.; Diken, M.; Maskos, M.; Morsbach, S.; Landfester, K.; Tenzer, S.; Barz, M.; Zentel, R. Polymeric Nanoparticles with Neglectable Protein Corona. Small, 2020, 16(18), 1907574. doi: 10.1002/smll.201907574
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