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Bis-ANS, protein conformation probe
| 貨號 | 數量 | 價格 | 交貨時間 | 購買此產品 |
|---|---|---|---|---|
| 4381-5mg | 5 mg | $159 | 現貨 | |
| 4381-25mg | 25 mg | $397 | 現貨 |
Bis-ANS is a high-affinity fluorescent probe for nonpolar cavities in proteins. Its hydrophobic phenyl and naphthyl rings interact noncovalently with proteins and protein degradation products.
As with other anilinonaphthalene sulfonates (ANS), bis-ANS is essentially nonfluorescent in water but becomes noticeably fluorescent in a nonpolar environment. When free, bis-ANS has an excitation maximum at 390 nm and an emission maximum at 523 nm but undergoes a blue shift with an increase in fluorescence intensity when bound to protein.
Bis-ANS is frequently used to monitor the formation of protein aggregates and indicate protein folding and conformational changes. The dye is also used to detect Aβ fibers.
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sulfo-Cyanine3 NHS酯 (sulfo-Cyanine3 NHS ester)
水溶性磺基-Cyanine3琥珀醯亞胺酯 (SE) 活化酯，用於氨基生物分子標記。Hoechst 34580，藍色螢光核酸染色劑 (Hoechst 34580, blue fluorescent nucleic acid stain)
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The cationic carbocyanine dye that is widely used as an indicator of mitochondrial membrane potential to study apoptosis and monitor the health of mitochondria.General properties
| Appearance: | light yellow-green crystals |
| Molecular weight: | 672.87 |
| CAS number: | 65664-81-5 |
| Molecular formula: | C32H22K2N2O6S2 |
| IUPAC name: | dipotassium;8-anilino-5-(4-anilino-5-sulfonatonaphthalen-1-yl)naphthalene-1-sulfonate |
| Solubility: | DMF: 30 mg/ml, DMSO: 30 mg/ml, ethanol: slightly soluble, PBS (pH 7.2): 5 mg/ml |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | 下載 |
| 產品規格 |
Spectral properties
| Excitation/absorption maximum, nm: | 396 (free), 401 (complex) |
| Emission maximum, nm: | 508 (free), 488 (complex) |
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
短連結 - hk.lumiprobe.com/sh/p/cI
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