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Bis-ANS, protein conformation probe
| 貨號 | 數量 | 價格 | 交貨時間 | 購買此產品 |
|---|---|---|---|---|
| 4381-5mg | 5 mg | $159 | 現貨 | |
| 4381-25mg | 25 mg | $397 | 現貨 |
Bis-ANS is a high-affinity fluorescent probe for nonpolar cavities in proteins. Its hydrophobic phenyl and naphthyl rings interact noncovalently with proteins and protein degradation products.
As with other anilinonaphthalene sulfonates (ANS), bis-ANS is essentially nonfluorescent in water but becomes noticeably fluorescent in a nonpolar environment. When free, bis-ANS has an excitation maximum at 390 nm and an emission maximum at 523 nm but undergoes a blue shift with an increase in fluorescence intensity when bound to protein.
Bis-ANS is frequently used to monitor the formation of protein aggregates and indicate protein folding and conformational changes. The dye is also used to detect Aβ fibers.
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花青3B四嗪 (Cyanine3B tetrazine)
Cyanine3B 染料四嗪衍生物，用於與張力烯烴和末端烯烴進行 IEDDA 偶聯。AF 647 DBCO
是遠紅螢光團 AF 647 的二苯並環辛炔（DBCO、ADIBO）衍生物，用於標記活細胞、整個生物體和無生命樣品中含疊氮基團的生物分子。AF 488 TCO
含有 AF 488 的反式環辛烯 (TCO) 衍生物，可通過逆電子需求Diels-Alder環加成反應 (IEDDA) 與四嗪偶聯。General properties
| Appearance: | light yellow-green crystals |
| Molecular weight: | 672.87 |
| CAS number: | 65664-81-5 |
| Molecular formula: | C32H22K2N2O6S2 |
| IUPAC name: | dipotassium;8-anilino-5-(4-anilino-5-sulfonatonaphthalen-1-yl)naphthalene-1-sulfonate |
| Solubility: | DMF: 30 mg/ml, DMSO: 30 mg/ml, ethanol: slightly soluble, PBS (pH 7.2): 5 mg/ml |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | 下載 |
| 產品規格 |
Spectral properties
| Excitation/absorption maximum, nm: | 396 (free), 401 (complex) |
| Emission maximum, nm: | 508 (free), 488 (complex) |
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
短連結 - hk.lumiprobe.com/sh/p/cI
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