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DusQ® 1 CPG 1000

CPG modifier solid supports DusQ® 1

貨號	數量	價格	交貨時間
14960	100 mg	$144	現貨
34960	500 mg	$530	現貨
44960	1 g	$960	現貨
54960	5 g	請查詢	現貨

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This support with a pore size of 1000 Å is intended for the automated synthesis of oligonucleotides of up to 120 bases in length modified with DusQ 1 dark quencher at the 3’ end.

Non-fluorescent DusQ 1 quencher exhibits the strongest absorption within the range of 480 to 580 nm; its absorption maximum is at 534 nm. It is suitable for quenching (a combination of static and dynamic quenching) of many fluorophores, including Biosearch Blue™, Marina Blue™, Edans, Bothell Blue, FAM™, JOE™, VIC™, R6G, HEX™, TET™ and Yakima Yellow™. It can be used for the synthesis of hybridization probes such as TaqMan, Molecular Beacon, Scorpion.

Usage

Coupling: Standard conditions identical to normal nucleobases.

Deprotection: 2 hours at room temperature using concentrated ammonia or 10 min at 65 °C using AMA mixture, concentrated aqueous ammonia/40% methylamine (1:1). Deprotection conditions depend on oligonucleotide composition and nucleobase protecting groups, as well as additional modifications, if present.

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Alkyne dT phosphoramidite

Phosphoramidite modifier for synthesizing oligonucleotides containing alkyne modification in the middle of the chain.

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DusQ® 3 CPG 500

DusQ® 3 is a dark quencher for far red and near infrared dyes like Cyanine5.5. This is a controlled pore glass solid support for the synthesis of oligonucleotides with the quencher attached to 3′-terminus.

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生物素亞磷酰胺（羥基脯氨醇）[Biotin phosphoramidite (hydroxyprolinol)]

生物素亞磷酰胺用於合成生物素化的寡核苷酸。含有二甲氧基三苯甲基基團。

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General properties

Appearance:	red beads
Quality control:	NMR ¹H and HPLC-MS (95%) of bound reagent, loading measurement, functional testing in oligo synthesis.
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	下載
	產品規格

Spectral properties

Excitation/absorption maximum, nm:	522
ε, L⋅mol⁻¹⋅cm⁻¹:	27300
CF₂₆₀:	0.17
CF₂₈₀:	0.10

Oligo synthesis details

Pore size, Å:	1000
Typical loading, umol/g:	30−50

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.