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AmdU (5-Azidomethyl-2'-deoxyuridine)

貨號 數量 價格 交貨時間
B1540 5 mg $120 現貨
D1540 25 mg $255 現貨
F1540 100 mg $890 現貨
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Azidomethyl-dU (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similar to EdU.

In contrast to EdU which needs to be further modified with azides in the presence of the copper catalyst, AmdU can also react in the absence of copper catalyst using SPAAC click chemistry with strained cycloalkynes, such as cyclooctynes. This enables the detection of nascent DNA in benign, copper-free conditions.

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THPTA配體

THPTA 是 Cu(I) 催化點擊化學的水溶性配體。該配體使銅穩定在 Cu(I) 氧化態。由於水溶性高,與該配體的反應不需要有機共溶劑。

銅 (II)-TВTA 催化緩衝液,1.5x (Copper(II)-TВTA catalytic buffer, 1.5x)

即用型催化緩衝液含有銅(II) 和 TBTA 配體。適用於核酸和小分子的點擊化學修飾。

Cyanine3 DBCO

Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper-free click chemistry.

General properties

Appearance: white / off white solid
Molecular weight: 283.24
CAS number: 59090-48-1
Molecular formula: C10H13N5O5
IUPAC name: 5-Azidomethyl-2'-deoxyuridine
Solubility: in water, alcohols, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
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