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Alkyne dT phosphoramidite

炔烴 Oligonucleotide synthesis Click chemistry Phosphoramidites

貨號	數量	價格	交貨時間
1897-100mg	100 mg	$330 $195	現貨
1897-1g	1 g	$2590 $1250	現貨
1897-5g	5 g	$9900 $2850	現貨

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This reagent is designed for the synthesis of oligonucleotides bearing triple bond (alkyne) in the middle of the chain. Alkyne is attached to the deoxyuridine fragment, and it does not interfere with the hybridization of the complementary strand. This allows the preparation of modified oligonucleotide probes bearing fluorescent dyes, quenchers, and other fragments attached to the middle of the chain by virtue of copper-catalyzed Click chemistry reaction with various azides.

This phosphoramidite is solid, so it is easy to dispense and handle. It is compatible with the standard deblocking conditions.

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炔酰胺、羥基脯氨醇 (Alkyne amidite, hydroxyprolinol)

用於將乙炔基團摻入寡聚物中的乙炔酰胺。

銅(II)-TBTA絡合物 (Copper(II)-TBTA complex)

點擊反應的催化劑。一種穩定的銅 (II) 絡合物，使用還原劑，可原位轉化為一價銅 (I)。該絡合物可用於制備任何組成的反應緩衝液。

生物素亞磷酰胺（羥基脯氨醇）[Biotin phosphoramidite (hydroxyprolinol)]

生物素亞磷酰胺用於合成生物素化的寡核苷酸。含有二甲氧基三苯甲基基團。

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General properties

Appearance:	off white solid
Mass spec M+ increment:	437.1
Molecular weight:	877.96
Molecular formula:	C₄₈H₅₆N₅O₉P
Solubility:	good in acetonitrile, DCM
Quality control:	NMR ¹H, NMR ³¹P, HPLC-MS
Storage conditions:	Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	下載
	產品規格

Oligo synthesis details

Diluent:	acetonitrile
Coupling conditions:	standard coupling, identical to normal nucleobases
Cleavage conditions:	ammonia, 2 h at room temperature
Deprotection conditions:	identical to protected nucleobases

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.