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Alkyne dT phosphoramidite

貨號 數量 價格 交貨時間
1897-100mg 100 mg $330 $195 現貨
1897-1g 1 g $2590 $1250 現貨
1897-5g 5 g $9900 $2850 現貨
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This reagent is designed for the synthesis of oligonucleotides bearing triple bond (alkyne) in the middle of the chain. Alkyne is attached to the deoxyuridine fragment, and it does not interfere with the hybridization of the complementary strand. This allows the preparation of modified oligonucleotide probes bearing fluorescent dyes, quenchers, and other fragments attached to the middle of the chain by virtue of copper-catalyzed Click chemistry reaction with various azides.

This phosphoramidite is solid, so it is easy to dispense and handle. It is compatible with the standard deblocking conditions.

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TBTA ligand

TBTA is one of the most widely used water-insoluble ligands for copper-catalyzed azide-alkyne cycloadditions (CuAAC).

炔酰胺、羥基脯氨醇 (Alkyne amidite, hydroxyprolinol)

用於將乙炔基團摻入寡聚物中的乙炔酰胺。

Cyanine5 NHS 酯 (Cyanine5 NHS ester)

胺反應性 Cyanine5 活化酯,用於標記蛋白質、肽和其他分子。

General properties

Appearance: off white solid
Mass spec M+ increment: 437.1
Molecular weight: 877.96
Molecular formula: C48H56N5O9P
Solubility: good in acetonitrile, DCM
Quality control: NMR 1H, NMR 31P, HPLC-MS
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: 下載
產品規格

Oligo synthesis details

Diluent: acetonitrile
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases
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