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AF 568 DBCO

AF 568 環炔烴 Copper-free click chemistry

貨號	數量	價格	交貨時間
1158F0	1 mg	$140	現貨
2158F0	5 mg	$450	現貨
4158F0	25 mg	$1460	現貨
5158F0	50 mg	$1890	現貨
6158F0	100 mg	$2990	現貨

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Dibenzocyclooctyne (DBCO, DBCO, ADIBO) is one of the most reactive cycloalkynes for copper-free click reaction (SPAAC, strain-promoted azide-alkyne cycloaddition). The rate of interaction of DBCO with azides is significantly higher than that of other cyclooctynes, as well as Cu-catalyzed click reaction (CuAAC). Unlike other cyclooctynes, DBCO does not interact with tetrazines, which makes it possible to use it in bioorthogonal reactions together with trans-cyclooctenes and tetrazines.

AF 568 is a bright, photostable, and hydrophilic fluorophore that emits in the orange channel. The absorption maximum is 572 nm. The emission maximum is 598 nm.

AF 568 DBCO allows fluorescent labeling of azide-containing biomolecules inside living cells and whole organisms without the negative effect of copper ions on them, and inanimate samples.

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AF 568 alkyne

AF 568 derivative designed for fluorescence microscopy and flow cytometry. Pure 5-isomer.

Azide-PEG6-NHS ester

A hydrophilic bifunctional linker with azide and NHS ester function groups flanking PEG6 (hexaethylene glycol).

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AmdU (5-Azidomethyl-2'-deoxyuridine)

Azidomethyldeoxyuridine (AmdU) is an azide-contained nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain-promoted click reaction.

General properties

Appearance:	dark violet solid
Molecular weight:	1197.53
Molecular formula:	C₆₆H₈₀N₆O₁₁S₂
Quality control:	NMR ¹H and HPLC-MS (95+%)
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light.
MSDS:	下載
	產品規格

Spectral properties

Excitation/absorption maximum, nm:	572
ε, L⋅mol⁻¹⋅cm⁻¹:	94238
Emission maximum, nm:	598
Fluorescence quantum yield:	0.912

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.