此頁面上的某些內容不提供英文版本,將默認以當前可用的語言顯示。

FAM phosphoramidite, 5-isomer

貨號 數量 價格 交貨時間
2639-500mg
/ 置於8mL帶隔墊小瓶的易溶凍幹態
500 mg
– 
現貨
2639-1g
/ 置於20mL帶隔墊小瓶的易溶凍幹態
1 g
$190 $147
現貨
2639-5g
/ 置於30mL帶隔墊小瓶
5 g
$740 $629
現貨
2639-10g
/ 置於30mL帶隔墊小瓶
10 g
$1290 $970
現貨
2639-50g 50 g
請查詢
21 天
2639-100g 100 g
請查詢
21 天
Found better price? Let us know and we will propose the way forward!

Standard fluorescein (FAM) phosphoramidite for 5'-terminal oligonucleotide labeling, high isomeric purity single isomer. This highly purified amidite reagent ensures excellent coupling results with various synthesizers.

Samples and special offers are available for oligo manufacturers. Contact us for bulk supplies of this reagent.

顧客還購買了這個產品

銅 (II)-TВTA 催化緩衝液,1.5x (Copper(II)-TВTA catalytic buffer, 1.5x)

即用型催化緩衝液含有銅(II) 和 TBTA 配體。適用於核酸和小分子的點擊化學修飾。

銅(II)-TBTA絡合物 (Copper(II)-TBTA complex)

點擊反應的催化劑。一種穩定的銅 (II) 絡合物,使用還原劑,可原位轉化為一價銅 (I)。該絡合物可用於制備任何組成的反應緩衝液。

General properties

Appearance: off white solid
Molecular weight: 843.94
CAS number: 147566-42-5
Molecular formula: C46H58N3O10P
Solubility: Good solubility in acetonitrile and DCM
Quality control: NMR 1H and 31P, HPLC-MS (95+%), isomeric purity > 97%
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: 下載
產品規格

Spectral properties

Excitation/absorption maximum, nm: 492
ε, L⋅mol−1⋅cm−1: 72000
Emission maximum, nm: 517
Fluorescence quantum yield: 0.93
CF260: 0.22
CF280: 0.17

Oligo synthesis details

Diluent: acetonitrile
Coupling conditions: coupling time 10 min
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases; when AMA is used, deblock with ammonia alone for 30 min, then add methylamine

產品引用

  1. Zharkov, T. D.; Markov, O. V.; Zhukov, S. A.; Khodyreva, S. N.; Kupryushkin, M. S. Influence of Combinations of Lipophilic and Phosphate Backbone Modifications on Cellular Uptake of Modified Oligonucleotides. Molecules, 2024, 29(2), 452. doi: 10.3390/molecules29020452
  2. Bauer, I.; Ilina, E.; Zharkov, T.; Grigorieva, E.; Chinak, O.; Kupryushkin, M.; Golyshev, V.; Mitin, D.; Chubarov, A.; Khodyreva, S.; Dmitrienko, E. Self-Penetrating Oligonucleotide Derivatives: Features of Self-Assembly and Interactions with Serum and Intracellular Proteins. Pharmaceutics, 2023, 15(12), 2779. doi: 10.3390/pharmaceutics15122779
  3. Petrunina, N.A.; Lebedev, V.V.; Kirillova, Y.G.; Aralov, A..V.; Varizhuk, A.M.; Sardushkin, M.V. DNA Intercalated Motifs with Non-Nucleoside Inserts. Russian Journal of Bioorganic Chemistry, 2021, 47(6), 1341–1344. doi: 10.1134/S1068162021060212
已添加您的物品. 查看您的 購物車繼續結賬
物品數量不正確.