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(SA) Succinylacetone-d6
| 貨號 | 數量 | 價格 | 交貨時間 | 購買此產品 |
|---|---|---|---|---|
| 4337-500ug | 0.50 mg | $259 | 12 天 |
Succinylacetone is a product of tyrosine catabolism and an inhibitor of heme biosynthesis. Succinylacetone (SA) testing in dried neonatal blood spots, followed by quantitation of SA in blood or urine in high-risk neonates, has excellent sensitivity and specificity for the diagnosis of tyrosinemia type 1 [1]. Succinylacetone also serves as a tool for studying the defects of heme synthesis on cellular processes.
[1] Kehar M., Sen Sarma M., Seetharaman J., Jimenez Rivera C., Chakraborty P. Decoding hepatorenal tyrosinemia type 1: Unraveling the impact of early detection, NTBC, and the role of liver transplantation. Can Liver J. 2024. 7(1). P.54-63.
General properties
| Appearance: | white solid |
| Molecular weight: | 160.21 |
| Molecular formula: | C7H4D6N2O2 |
| Solubility: | in water |
| Quality control: | NMR 1H and HPLC-MS (95+ %, D: 98+ %) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | 下載 |
| 產品規格 |
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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