DBCO-NHS 酯

NHS酯類環炔烴 Protein labeling Copper-free click chemistry Crosslinking

貨號	數量	價格	交貨時間
34720	10 mg	$80	現貨
44720	25 mg	$110	現貨
54720	50 mg	$135	現貨
64720	100 mg	$210 $178	現貨
94720	1 g	$1000 $970	現貨
K4720	5 g	$3570 $2990	現貨

Found better price? Let us know and we will propose the way forward!

二苯並環辛炔 (ADIBO、DBCO) 是應變促進的炔疊氮化環加成反應(SPAAC)中反應性最強的環炔烴之一，這是一種無銅點擊化學反應。 DBCO 立即與疊氮化物發生反應。該反應速率遠高於銅催化反應以及與許多其他環辛炔的反應。與一些其他環辛烯不同，DBCO 不與四嗪反應 - 這允許疊氮化物與 DBCO 以及反式環辛烯與四嗪進行正交共軛。這種胺反應性 NHS 酯可以將反應性部分輕松連接到幾乎任何伯胺或仲胺基團，例如蛋白質、肽或小分子胺。

以
ChemDraw 格式下載

建議協議

NHS Ester Labeling of Biomolecules Containing Primary Amino Groups

計算機

蛋白質標記計算器

外观:
质谱 M+ 增量:	315.1
分子量:	430.45
CAS 编号:	1384870-47-6
分子式:	C₂₅H₂₂N₂O₅
IUPAC 名称:	6-{2-Azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-6-oxohexanamide
溶解度:
质量控制:
储存条件:
MSDS:	下載
	產品規格

產品引用

Mitchell, M.I.; Ben‐Dov, I.Z.; Ye, K.; Liu, C.; Shi, M.; Sadoughi, A.; Shah, C.; Siddiqui, T.; Okorozo, A.; Gutierrez, M.; Unawane, R.; Biamonte, L.; Parihk, K.; Spivack, S.; Loudig, O. Exhaled breath condensate contains extracellular vesicles (EVs) that carry miRNA cargos of lung tissue origin that can be selectively purified and analyzed. Journal of Extracellular Vesicles, 2024, 13(4), e12440. doi: 10.1002/jev2.12440
Mitchell, M.I.; Ben-Dov, I.Z.; Liu, C.; Wang, T.; Hazan, R.B.; Bauer, T.L.; Zakrzewski, J.; Donnelly, K.; Chow, K.; Ma, J.; Loudig, O. Non-invasive detection of orthotopic human lung tumors by microRNA expression profiling of mouse exhaled breath condensates and exhaled extracellular vesicles. Extracellular Vesicles and Circulating Nucleic Acids, 2024, 5(1), 138-64. doi: 10.20517/evcna.2023.77
Mitchell, M.I.; Khalil, M.; Ben-Dov, I.Z.; Alverez-Perez, J.; Illsley, N.P.; Zamudio, S.; Al-Khan, A.; Loudig, O. Customizing EV-CATCHER to Purify Placental Extracellular Vesicles from Maternal Plasma to Detect Placental Pathologies. International Journal of Molecular Sciences, 2024, 25(10), 5102. doi: 10.3390/ijms25105102
Gabold, B.; Adams, F.; Brameyer, S.; Jung, K.; Ried, C. L.; Merdan, T.; Merkel, O. M. Transferrin-Modified Chitosan Nanoparticles for Targeted Nose-to-Brain Delivery of Proteins. Drug Deliv. and Transl. Res., 2023, 13(3), 822–838. doi: 10.1007/s13346-022-01245-z