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Cyanine7 azide

Cyanine7 Azides Click chemistry Near infrared (NIR) imaging

貨號	數量	價格	交貨時間
15030	100 uL, 10 mM/DMSO	–	現貨
35030	500 uL, 10 mM/DMSO	$199	現貨
45030	1 mL, 10 mM/DMSO	$495	現貨
A5030	1 mg	–	現貨
B5030	5 mg	$199	現貨
C5030	10 mg	$297	現貨
D5030	25 mg	$495	現貨
E5030	50 mg	$895	現貨

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Cyanine7 azide is a near-infrared fluorescent dye azide for click chemistry labeling, an analog of Cy7® azide.

This product can be used for the incorporation of Cyanine7 into various alkynylated biomolecules via click chemistry. Post-synthetic modification of oligonucleotides is also possible with this azide.

Cyclohexane-bridged polymethyne chain allows for 20% increase in quantum yield (compared to parent non-bridged structure).

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General properties

Appearance:	green powder / solution
Molecular weight:	667.33
CAS number:	1557149-65-1 (chloride), 1557397-59-7
Molecular formula:	C₄₀H₅₁ClN₆O
Solubility:	soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS:	下載
	產品規格

Spectral properties

Excitation/absorption maximum, nm:	750
ε, L⋅mol⁻¹⋅cm⁻¹:	199000
Emission maximum, nm:	773
Fluorescence quantum yield:	0.3
CF₂₆₀:	0.022
CF₂₈₀:	0.029

產品引用

Shen, W.; You, T.; Xu, W.; Xie, Y.; Wang, Y.; Cui, M. Rapid and Widespread Distribution of Intranasal Small Extracellular Vesicles Derived from Mesenchymal Stem Cells throughout the Brain Potentially via the Perivascular Pathway. Pharmaceutics, 2023, 15(11), 2578. doi: 10.3390/pharmaceutics15112578
Zeng, Y.; Shen, Y.; Wu, S.; Cai, L.; Wang, Z.; Cai, K.; Shen, J.; Hii Ru Yie, K.; Zhang, H.; Xu, L.; Liu, J. Bone-Targeting PLGA Derived Lipid Drug Delivery System Ameliorates Bone Loss in Osteoporotic Ovariectomized Rats. Materials & Design, 2022, 221, 110967. doi: 10.1016/j.matdes.2022.110967
Roberts, S.; Khera, E.; Choi, C.; Navaratna, T.; Grimm, J.; Thurber, G.M.; Reiner, T. Optoacoustic imaging of Glucagon-like Peptide 1 Receptor with a near-infrared exendin-4 analog. Journal of Nuclear Medicine, 2021, 62(6), 839–848. doi: 10.2967/jnumed.120.252262
Thauvin, C.; Maudens, P.; Allémann, E. Microwave-assisted synthesis of self-assembling bi-functionalizable amphiphilic diblock copolymers. Journal of Drug Delivery Science and Technology, 2021, 61, 102255. doi: 10.1016/j.jddst.2020.102255