Cyanine5炔烴 (Cyanine5 alkyne)

貨號	數量	價格	交貨時間
A30B0	1 mg	$125	現貨
B30B0	5 mg	$260	現貨
C30B0	10 mg	$325	現貨
D30B0	25 mg	$510	現貨
E30B0	50 mg	$895	現貨
F30B0	100 mg	$1490	現貨

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Cyanine5 是 Cy5® 的類似物，是深色和光穩定的熒光團。花青5炔可以通過與疊氮化合物的點擊化學反應連接到各種分子上。

該炔烴不溶於水，但在反應前可將其溶解在 DMF 或 DMSO 中，並添加到水相反應混合物中。通過我們的標記方案labeling protocol，標記反應非常高效而且高產。

帶有疊氮基的各種底物均可用於標記，包括疊氮基標記的生物分子、聚合物和固體表面。

以
ChemDraw 格式下載

建議協議

Conjugation of Alkyne- or Azide-modified Proteins with Dye Azides or Alkynes

計算器

Solution calculator

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Ascorbic acid

Ascorbic acid is a reducing agent converting copper(II) into a monovalent form that catalyzes the click reaction.

TAMRA alkyne, 6-isomer

Terminal alkyne for copper-catalyzed click chemistry. Tetramethylrhodamine (TAMRA) is a rhodamine dye which is popular in qPCR and other applications. TAMRA is a also a FRET acceptor for FAM.

ROX alkyne, 5-isomer

An alkyne derivative of bright red-emitting dye ROX (Rhodamine X, Rhodamine 101) for copper-catalyzed click chemistry bioconjugation. Pure 5-isomer.

外观:	深藍色粉末
分子量:	556.18
CAS 编号:	1223357-57-0
分子式:	C₃₅H₄₂ClN₃O
溶解度:
质量控制:
储存条件:
MSDS:	下載
	產品規格

激发/吸收极大值，纳米:	646
ε, 摩尔吸光系数，cm⁻¹:	250000
发射极大值，纳米:	662
荧光量子产率:	0.2
CF₂₆₀:	0.03
CF₂₈₀:	0.04

產品引用

Peng, Y.-J.; Nanduri, J.; , Wang, N.; Kumar, G.K.; Bindokas, V.;,Paul, B.D.; Chen, X.; Fox, A.P.; Vignane, T.; Filipovic, M.R.; Prabhakar, N.R. Hypoxia sensing requires H2S-dependent persulfidation of olfactory receptor 78. Science Advances, 2023, 9(27), eadf302. doi: 10.1126/sciadv.adf3026
Drekolia, M.-K.; Karantanou, C.; Wittig, I.; Li, Y.; Fuhrmann, D.C.; Brüne, B.; Katsouda, A.; Hu, J.; Papapetropoulos, A.; Bibli, S.-I. Loss of cardiac mitochondrial complex I persulfidation impairs NAD + homeostasis in aging. Redox Biology, 2023, 69, 103014. doi: 10.1016/j.redox.2023.103014
Sokolova, V.; Ebel, J.-F.; Kollenda, S.; Klein, K.; Kruse, B.; Veltkamp, C.; Lange, C. M.; Westendorf, A. M.; Epple, M. Uptake of Functional Ultrasmall Gold Nanoparticles in 3D Gut Cell Models. Small, 2022, 18(31), 2201167. doi: 10.1002/smll.202201167
Sargiacomo, C.; Stonehouse, S.; Moftakhar, Z.; Sotgia, F.; Lisanti, M.P. MitoTracker Deep Red (MTDR) Is a Metabolic Inhibitor for Targeting Mitochondria and Eradicating Cancer Stem Cells (CSCs), With Anti-Tumor and Anti-Metastatic Activity In Vivo. Frontiers in Oncology, 2021, 11, 678343. doi: 10.3389/fonc.2021.678343