Cyanine3B TCO
| 貨號 | 數量 | 價格 | 交貨時間 | 購買此產品 |
|---|---|---|---|---|
| 139H0 | 1 mg |
$590.00
|
現貨 |
Cyanine3B TCO is a derivative of the Cyanine3B dye functionalized with trans-cyclooctene (TCO) for rapid and selective conjugation to tetrazine-containing biomolecules.
The dye belongs to the cyanine family of orange-red fluorophores and is characterized by high molar absorptivity, high fluorescence quantum yield, and improved photostability compared to conventional Cyanine3. Cyanine3B provides bright and stable fluorescence signals in fluorescence microscopy, flow cytometry, FRET experiments, and super-resolution imaging applications.
The TCO moiety reacts rapidly and selectively with tetrazines without the need for catalysts via the inverse electron-demand Diels—Alder (IEDDA) reaction, enabling biomolecule labeling under mild conditions, including in live cells. The reaction features by fast kinetics, excellent biocompatibility, and minimal background signal.
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General properties
| Appearance: | red powder |
| Molecular weight: | 811.06 |
| Molecular formula: | C46H58N4O7S |
| Solubility: | DMSO, DMF, acetonitrile |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light. |
| MSDS: | 下載 |
| 產品規格 |
Spectral properties
| Excitation/absorption maximum, nm: | 559 |
| ε, L⋅mol−1⋅cm−1: | 121000 |
| Emission maximum, nm: | 571 |
| Fluorescence quantum yield: | 0.68 |
| CF260: | 0.044 |
| CF280: | 0.077 |
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