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Alkyne-PEG4-maleimide

貨號 數量 價格 交貨時間
2002-100mg 100 mg $150 現貨
2002-1g 1 g $590 現貨
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When proteins or other sensitive biomolecules need to be conjugated, polyethyleneglycol (PEG) linkers are a great choice. They provide hydrophilicity and maintain separation between conjugated molecules. This linker based on PEG4, has length of 14Å (1.4 nm). Heterobifunctional linkers carrying different reactive groups can be used to prepare cross-conjugates between different molecules.

Maleimide functional group is especially useful, because they can label proteins site specifically. Most proteins have only limited number of cysteine residues that selectively react with maleimides. Alkyne group can be then conjugated with azides in a selective copper-catalyzed process, CuAAC (copper-catalyzed alkyne-azide cycloaddition).

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炔基馬來酰亞胺 (Alkyne maleimide)

馬來酰亞胺試劑用於將炔基官能團連接到蛋白質、多肽和其它含有 SH(硫醇)基團的分子上,包括半胱氨酸殘基。

Alkyne hydrazide

Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.

磺基-Cyanine7.5 NHS酯 (sulfo-Cyanine7.5 NHS ester)

一種用於活體成像的水溶性近紅外發射染料。 sulfo-Cyanine7.5 是吲哚菁綠 (ICG) 的類似物,具有較高的發射量子產率和連接臂。

General properties

Appearance: yellow oil
Mass spec M+ increment: 311.3
Molecular weight: 311.33
CAS number: 1262681-30-0
Molecular formula: C15H21NO6
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
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