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Alkyne-PEG3-NHS ester

貨號 數量 價格 交貨時間
2298-1g 1 g $490 現貨
2298-5g 5 g $980 現貨
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Alkyne-PEG3-NHS ester is a bifunctional molecule containing NHS ester and alkyne functional groups. NHS ester group is used for the labeling of amine groups, like lysine and terminal NH2, in proteins and peptides. The terminal alkyne group is useful for copper-catalyzed click chemistry (CuAAC) or Sonogashira coupling.

PEG3 is a hydrophilic linker providing a good separation between the parts of the conjugate.

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AmdU (5-Azidomethyl-2'-deoxyuridine)

Azidomethyldeoxyuridine (AmdU) is an azide-contained nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain-promoted click reaction.

General properties

Appearance: colorless to yellowish oil
Molecular weight: 357.36
CAS number: 1428629-70-2
Molecular formula: C16H23NO8
IUPAC name: 2,5-Dioxo-1-pyrrolidinyl 3-(2-{2-[2-(2-propynyloxy)ethoxy]ethoxy}ethoxy)propionate
Solubility: good in water and polar organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
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