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Hexynoic acid NHS ester

貨號 數量 價格 交貨時間
41720 25 mg $95 現貨
51720 50 mg $180 現貨
61720 100 mg $290 現貨
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Hexynoic acid NHS ester is an alkyne-containing NHS ester for the modification of biomolecules. Alkyne groups for copper-catalyzed click chemistry reaction are nearly never encountered in natural molecules. However, this NHS ester allows to attach alkyne groups to amino groups, which are ubiquitous in nature, and which are present in proteins, peptides, synthetic amino-DNA and numerous small molecules. Alkyne groups can be subsequently modified and conjugated by copper-catalyzed click reaction.

This reagent is a derivative of hexynoic acid.

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BDP 576/589 NHS 酯 (BDP 576/589 NHS ester)

BDP 576/589 NHS 酯(BODIPY™ 576/589 類似物)是一種明亮的疏水性染料,發射在橙色光譜範圍內。它可用於熒光各向異性分析。
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Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono-reactive dye for protein labeling.

Cyanine3.5 NHS酯 (Cyanine3.5 NHS ester)

Cyanine3.5染料NHS酯的衍生物。
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General properties

Appearance: yellowish oil / off white crystals
Mass spec M+ increment: 94.0
Molecular weight: 209.20
CAS number: 906564-59-8
Molecular formula: C10H11NO4
IUPAC name: 5-​Hexynoic acid, 2,​5-​dioxo-​1-​pyrrolidinyl ester
Solubility: good in organic solvents (DMF, DMSO, DCM)
Quality control: NMR 1H 95+%
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: 下載
產品規格

產品引用

  1. Monakhova, M. V.; Kubareva, E. A.; Kolesnikov, K. K.; Anashkin, V. A.; Kosaretskiy, E. M.; Zvereva, M. I.; Romanova, E. A.; Friedhoff, P.; Oretskaya, T. S.; Zatsepin, T. S. Reactive Acrylamide-Modified DNA Traps for Accurate Cross-Linking with Cysteine Residues in DNA–Protein Complexes Using Mismatch Repair Protein MutS as a Model. Molecules, 2022, 27(8), 2438. doi: 10.3390/molecules27082438
  2. Zanon, P.R.A.; Yu, F.; Musacchio, P.; Lewald, L.; Zollo, M.; Krauskopf, K.; Mrdović, D.; Raunft, P.; Maher, T.E.; Cigler, M.; Chang, C.; Lang, K.; Toste, F.D.; Nesvizhskii, A.I.; Hacker, S.M. Profiling the proteome-wide selectivity of diverse electrophiles. ChemRxiv, 2021, preprint. doi: 10.33774/chemrxiv-2021-w7rss-v2
  3. Kleinpenning, F.; Steigenberger, B.; Wu, W.; Heck, A.J.R. Fishing for newly synthesized proteins with phosphonate-handles. Nature Communications, 2020, 11, 3244. doi: 10.1038/s41467-020-17010-0
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