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Reapack® ETT activator

5-(Ethylthio)-1H-tetrazole, also known as ETT, is a chemical compound widely used as an activator in the synthesis of oligonucleotides. ETT is an effective activator for nucleoside phosphoramidites, facilitating their condensation with nucleosides to form dinucleoside phosphates during the synthesis of oligonucleotides. The ethylthio group makes ETT significantly more acidic than tetrazole, enhancing its ability as an activator.

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General properties

Appearance: white powder
Molecular weight: 130.18
CAS number: 89797-68-2, 618-305-8
Molecular formula: C3H6N4S
IUPAC name: 5-ethylsulfanyl-2H-tetrazole
Solubility: acetonitrile
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
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