(E/Z)-4-Hydroxytamoxifen
貨號 | 數量 | 價格 | 交貨時間 | 購買此產品 |
---|---|---|---|---|
3669-10mg | 10 mg | $60 | 現貨 | |
3669-50mg | 50 mg | $209 | 現貨 |
(E/Z)-4-Hydroxytamoxifen (4-OHT, cis/trans-4-hydroxytamoxifen, afimoxifene) is a selective estrogen receptor (ER) modulator, an active metabolite of tamoxifen. 4-Hydroxytamoxifen is widely used as a research tool for inducible genome manipulation.
4-Hydroxytamoxifen is used in the inducible Cre-LoxP system to control CreER/CreERT2 recombinase activity and trigger tissue-specific gene expression or genome/genetic modification (e.g., gene deletion). 4-Hydroxytamoxifen is a part of the TRAP/TRAP2 (targeted recombination in active populations) systems providing genetic access to neuron activity. It is also used in CRISPR/Cas9 gene editing to activate inactivated Cas9 nuclease.
Also, 4-Hydroxytamoxifen was reported to be an intramembranous lipid peroxidation inhibitor, exhibiting peroxyl radical scavenging activity.
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綠色Synapto探針 (SynaptoProbe Green)
綠色Synapto探針 (SynaptoProbe Green)DREADD agonist 21 dihydrochloride
An agonist for selective activation of hM3Dq (excitatory) and hM4Di (inhibitory) DREADDs. A widely used chemogenetic tool for remotely controlling neuronal activity.AF 488 amine
AF 488 dye with a terminal amino group with emission in the green region of the spectrum.General properties
Appearance: | white solid |
Molecular weight: | 387.52 |
CAS number: | 68392-35-8 |
Molecular formula: | C26H29NO2 |
IUPAC name: | 4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol |
Solubility: | DMF, Ethanol, DMSO |
Quality control: | NMR 1H and HPLC-MS (95+%) |
Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
MSDS: | 下載 |
產品規格 |