(E/Z)-4-Hydroxytamoxifen
| 貨號 | 數量 | 價格 | 交貨時間 | 購買此產品 |
|---|---|---|---|---|
| 3669-10mg | 10 mg | $60 | 現貨 | |
| 3669-50mg | 50 mg | $209 | 現貨 |
(E/Z)-4-Hydroxytamoxifen (4-OHT, cis/trans-4-hydroxytamoxifen, afimoxifene) is a selective estrogen receptor (ER) modulator, an active metabolite of tamoxifen. 4-Hydroxytamoxifen is widely used as a research tool for inducible genome manipulation.
4-Hydroxytamoxifen is used in the inducible Cre-LoxP system to control CreER/CreERT2 recombinase activity and trigger tissue-specific gene expression or genome/genetic modification (e.g., gene deletion). 4-Hydroxytamoxifen is a part of the TRAP/TRAP2 (targeted recombination in active populations) systems providing genetic access to neuron activity. It is also used in CRISPR/Cas9 gene editing to activate inactivated Cas9 nuclease.
Also, 4-Hydroxytamoxifen was reported to be an intramembranous lipid peroxidation inhibitor, exhibiting peroxyl radical scavenging activity.
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Cyanine5.5炔烴 (Cyanine5.5 alkyne)
Cyanine5.5 alkyne 是一種用於銅催化的點擊化學的NIR（近紅外）染料疊氮化物，
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氨基-11-ddUTP (Amino-11-ddUTP)
Amino-11-ddUTP 是一種用於修飾 DNA 的三磷酸鹽。
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AF 647 NHS 酯 (AF 647 NHS ester)
明亮的水溶性琥珀醯亞胺酯AF 647染料，用於蛋白質和抗體標記。General properties
| Appearance: | white solid |
| Molecular weight: | 387.52 |
| CAS number: | 68392-35-8 |
| Molecular formula: | C26H29NO2 |
| IUPAC name: | 4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol |
| Solubility: | DMF, Ethanol, DMSO |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | 下載 |
| 產品規格 |
產品引用
- Thi Duy Ngoc, N.; Yurchenko, E. A.; Thi Hoai Trinh, P.; Menchinskaya, E. S.; Thi Dieu, T. V.; Savagina, A. D.; Minin, A.; Thinh, P. D.; Khanh, H. H. N.; Thi Thanh Van, T.; Yurchenko, A. N. Secondary Metabolites of Vietnamese Marine Fungus Penicillium Chermesinum 2104NT-1.3 and Their Cardioprotective Activity. Regional Studies in Marine Science, 2024, 104003. doi: 10.1016/j.rsma.2024.104003
- Leshchenko, E.V.; Chingizova, E.A.; Antonov, A.S.; Shlyk, N.P.; Borkunov, G.V.; Berdyshev, D.V.; Chausova, V.E.; Kirichuk, N.N.; Khudyakova, Y.V.; Chingizov, A.R.; Kalinovsky, A.I.; Popov, R.S.; Kim, N.Y..; Chadova, K.A.; Yurchenko, E.A.; Isaeva, M.P.; Yurchenko, A.N. New Zosteropenillines and Pallidopenillines from the Seagrass-Derived Fungus Penicillium Yezoense KMM 4679. Marine Drugs, 2024, 22(7), 317. doi: 10.3390/md22070317
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